Literature DB >> 11975638

Asymmetric synthesis of substituted prolines from delta-amino beta-ketoesters. Methyl (2S,5R)-(+)-5-phenylpyrrolidine-2-carboxylate.

Franklin A Davis1, Tianan Fang, Rajesh Goswami.   

Abstract

[reaction: see text]. Metal carbenoid chemistry is used to convert delta-amino beta-ketoesters into 5-substituted 3-oxo prolines, which expands the utility of this class of polyfunctionalized chiral building blocks.

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Year:  2002        PMID： 11975638     DOI： 10.1021/ol025831j

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  Novel Entry to the Tricyclic Core of Stemofoline and Didehydrostemofoline.

Authors:  Jochen Dietz; Stephen F Martin
Journal:  Tetrahedron Lett       Date:  2011-04-27       Impact factor: 2.415

2.  Toward a total synthesis of the stemofoline alkaloids: Advancement of a 1,3-dipolar cycloaddition strategy.

Authors:  Charles S Shanahan; Nathan O Fuller; Bjoern Ludolph; Stephen F Martin
Journal:  Tetrahedron Lett       Date:  2011-08-10       Impact factor: 2.415

3.  Synthesis of polysubstituted pyrroles from sulfinimines (N-sulfinyl imines).

Authors:  Franklin A Davis; Kerisha A Bowen; He Xu; Venkata Velvadapu
Journal:  Tetrahedron       Date:  2008-05-05       Impact factor: 2.457

4.  Cytochrome P450-Catalyzed Insertion of Carbenoids into N-H Bonds.

Authors:  Z Jane Wang; Nicole E Peck; Hans Renata; Frances H Arnold
Journal:  Chem Sci       Date:  2014-02-01       Impact factor: 9.825

5.  Organocatalytic Enantioselective γ-Position-Selective Mannich Reactions of β-Ketocarbonyl Derivatives.

Authors:  Venkati Bethi; Fujie Tanaka
Journal:  Org Lett       Date:  2022-09-12       Impact factor: 6.072
  5 in total

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