Literature DB >> 11975625

Silyl-substituted amino acids: new routes to the construction of selectively functionalized peptidomimetics.

Haizhou Sun1, Kevin D Moeller.   

Abstract

[reaction: see text]. Silylated amino acids have been incorporated into peptides and then converted into N-acyliminium ions with the use of an anodic oxidation reaction. The result is a method for selectively incorporating conformational constraints or external nucleophiles within the peptide.

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Year:  2002        PMID： 11975625     DOI： 10.1021/ol025776e

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  Electrochemical Oxidation of Organic Molecules at Lower Overpotential: Accessing Broader Functional Group Compatibility with Electron-Proton Transfer Mediators.

Authors:  Fei Wang; Shannon S Stahl
Journal:  Acc Chem Res       Date:  2020-02-12       Impact factor: 22.384

Review 2.  The Shono-type electroorganic oxidation of unfunctionalised amides. Carbon-carbon bond formation via electrogenerated N-acyliminium ions.

Authors:  Alan M Jones; Craig E Banks
Journal:  Beilstein J Org Chem       Date:  2014-12-18       Impact factor: 2.883

Review 3.  Recent advances in Cu-catalyzed C(sp3)-Si and C(sp3)-B bond formation.

Authors:  Balaram S Takale; Ruchita R Thakore; Elham Etemadi-Davan; Bruce H Lipshutz
Journal:  Beilstein J Org Chem       Date:  2020-04-15       Impact factor: 2.883

4.  Constrained Dipeptide Surrogates: 5- and 7-Hydroxy Indolizidin-2-one Amino Acid Synthesis from Iodolactonization of Dehydro-2,8-diamino Azelates.

Authors:  Ramakotaiah Mulamreddy; William D Lubell
Journal:  Molecules       Date:  2021-12-23       Impact factor: 4.411

5.  Total synthesis of biseokeaniamides A-C and late-stage electrochemically-enabled peptide analogue synthesis.

Authors:  Yutong Lin; Lara R Malins
Journal:  Chem Sci       Date:  2020-07-30       Impact factor: 9.825
  5 in total

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