Literature DB >> 11975513

Isolation, structure elucidation, and absolute configuration of 26-deoxyactein from Cimicifuga racemosa and clarification of nomenclature associated with 27-deoxyactein.

Shao-Nong Chen1, Wenkui Li, Daniel S Fabricant, Bernard D Santarsiero, Andrew Mesecar, John F Fitzloff, Harry H S Fong, Norman R Farnsworth.   

Abstract

A new triterpene glycoside, 26-deoxyactein (1), along with two known compounds, 23-epi-26-deoxyactein (2), previously designated as "27-deoxyactein", and actein (3), were isolated from the roots/rhizomes of Cimicifuga racemosa. The structures and absolute stereochemistry of 1 and 2 were established by spectroscopic methods (FABMS, (1)H and (13)C NMR) and single-crystal X-ray data analysis.

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Year:  2002        PMID： 11975513     DOI： 10.1021/np010494t

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  24 in total

1.  Evaluation of the botanical authenticity and phytochemical profile of black cohosh products by high-performance liquid chromatography with selected ion monitoring liquid chromatography-mass spectrometry.

Authors:  Bei Jiang; Fredi Kronenberg; Paiboon Nuntanakorn; Ming-Hua Qiu; Edward J Kennelly
Journal:  J Agric Food Chem       Date:  2006-05-03       Impact factor: 5.279

Review 2.  The role of quality assurance and standardization in the safety of botanical dietary supplements.

Authors:  Richard B van Breemen; Harry H S Fong; Norman R Farnsworth
Journal:  Chem Res Toxicol       Date:  2007-03-16       Impact factor: 3.739

3.  In vitro serotonergic activity of black cohosh and identification of N(omega)-methylserotonin as a potential active constituent.

Authors:  Sharla L Powell; Tanja Gödecke; Dejan Nikolic; Shao-Nong Chen; Soyoun Ahn; Birgit Dietz; Norman R Farnsworth; Richard B van Breemen; David C Lankin; Guido F Pauli; Judy L Bolton
Journal:  J Agric Food Chem       Date:  2008-12-24       Impact factor: 5.279

4.  In vitro metabolic interactions between black cohosh (Cimicifuga racemosa) and tamoxifen via inhibition of cytochromes P450 2D6 and 3A4.

Authors:  Jinghu Li; Tanja Gödecke; Shao-Nong Chen; Ayano Imai; David C Lankin; Norman R Farnsworth; Guido F Pauli; Richard B van Breemen; Dejan Nikolić
Journal:  Xenobiotica       Date:  2011-08-09       Impact factor: 1.908

5.  Black cohosh (Actaea racemosa, Cimicifuga racemosa) behaves as a mixed competitive ligand and partial agonist at the human mu opiate receptor.

Authors:  Mee-Ra Rhyu; Jian Lu; Donna E Webster; Daniel S Fabricant; Norman R Farnsworth; Z Jim Wang
Journal:  J Agric Food Chem       Date:  2006-12-27       Impact factor: 5.279

6.  Fukinolic acid derivatives and triterpene glycosides from black cohosh inhibit CYP isozymes, but are not cytotoxic to Hep-G2 cells in vitro.

Authors:  Yue Huang; Bei Jiang; Paiboon Nuntanakorn; Edward J Kennelly; Stacy Shord; Temitope O Lawal; G B Mahady
Journal:  Curr Drug Saf       Date:  2010-04

Review 7.  Botanicals and Their Bioactive Phytochemicals for Women's Health.

Authors:  Birgit M Dietz; Atieh Hajirahimkhan; Tareisha L Dunlap; Judy L Bolton
Journal:  Pharmacol Rev       Date:  2016-10       Impact factor: 25.468

8.  Cimicifuga species identification by high performance liquid chromatography-photodiode array/mass spectrometric/evaporative light scattering detection for quality control of black cohosh products.

Authors:  Kan He; Guido F Pauli; Bolin Zheng; Huikang Wang; Naisheng Bai; Tangsheng Peng; Marc Roller; Qunyi Zheng
Journal:  J Chromatogr A       Date:  2006-03-02       Impact factor: 4.759

9.  Chlorination diversifies Cimicifuga racemosa triterpene glycosides.

Authors:  Shao-Nong Chen; David C Lankin; Dejan Nikolic; Daniel S Fabricant; Zhi-Zhen Lu; Benjamin Ramirez; Richard B van Breemen; Harry H S Fong; Norman R Farnsworth; Guido F Pauli
Journal:  J Nat Prod       Date:  2007-06-08       Impact factor: 4.050

10.  NMR based quantitation of cycloartane triterpenes in black cohosh extracts.

Authors:  Ayano Imai; David C Lankin; Tanja Gödecke; Shao-Nong Chen; Guido F Pauli
Journal:  Fitoterapia       Date:  2019-12-27       Impact factor: 2.882
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