Literature DB >> 11974993

The punctate midline myelotomy concept for visceral cancer pain control--case report and review of the literature.

R Becker1, S Gatscher, U Sure, H Bertalanffy.   

Abstract

INTRODUCTION: Nauta et al. first reported on a successful punctate midline myelotomy (PMM) at the spinal cord Th 10 level for the treatment of intractable pelvic cancer pain. CASE STUDY: The authors published another case history of a patient with multiple anaplastic carcinomas of the small intestine, peritoneal carcinosis and retroperitoneal lymphomas, suffering from severe visceral pain in the hypo-, meso-, and epigastrium. Nauta's PMM was successfully performed at the level Th 4. Narcotic medication was tapered from 30 mg i.v. morphine per hour preoperatively to 5 mg per hour within 5 days postoperatively. Pain intensity decreased from 10 to 2-3 on the visual analog scale. Only minor transient side effects appeared postoperatively. Pain reduction remained until the patient died from the extended disease five weeks later. DISCUSSION: Meanwhile Nauta et al. reported on 5 additional patients, in whom PMM led to a sufficient pain reduction. Another paper reported on sufficient control of visceral pain due to advanced stomach cancer after a modified Th 1-2 PMM.
CONCLUSION: PMM sufficiently controls not only pelvic visceral pain, but also visceral pain generated in the meso- and epigastrium. The findings support the concept of a midline dorsal column visceral pain pathway.

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Year:  2002        PMID: 11974993     DOI: 10.1007/978-3-7091-6105-0_17

Source DB:  PubMed          Journal:  Acta Neurochir Suppl        ISSN: 0065-1419


  3 in total

1.  The role of c-AMP-dependent protein kinase in spinal cord and post synaptic dorsal column neurons in a rat model of visceral pain.

Authors:  Jing Wu; Guangxiao Su; Long Ma; Xuan Zhang; Yongzhong Lei; Qing Lin; Haring J W Nauta; Junfa Li; Li Fang
Journal:  Neurochem Int       Date:  2007-01-25       Impact factor: 3.921

2.  TRPV1-Like Immunoreactivity in the Human Locus K, a Distinct Subregion of the Cuneate Nucleus.

Authors:  Marina Del Fiacco; Maria Pina Serra; Marianna Boi; Laura Poddighe; Roberto Demontis; Antonio Carai; Marina Quartu
Journal:  Cells       Date:  2018-07-08       Impact factor: 6.600

Review 3.  Effects of general anesthetics on visceral pain transmission in the spinal cord.

Authors:  Yun Wang; Jing Wu; Qing Lin; Hj Nauta; Yun Yue; Li Fang
Journal:  Mol Pain       Date:  2008-10-30       Impact factor: 3.395

  3 in total

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