Literature DB >> 11973135

Influence of effector molecules on the CD8(+) T cell response to infection.

John T Harty1, Vladimir P Badovinac.   

Abstract

Expansion and contraction of antigen-specific CD8(+) T cells after infection or vaccination results in stable memory. Recent evidence demonstrates that anti-microbial effector molecules such as perforin and IFN-gamma regulate specific aspects of CD8(+) T cell homeostasis by mechanisms that may be dependent or independent of pathogen clearance.

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Year:  2002        PMID: 11973135     DOI: 10.1016/s0952-7915(02)00333-3

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN: 0952-7915            Impact factor:   7.486


  31 in total

1.  Perforin plays an unexpected role in regulating T-cell contraction during prolonged Listeria monocytogenes infection.

Authors:  Nathan W Schmidt; Aaruni Khanolkar; Lisa Hancox; Jonathan W Heusel; John T Harty
Journal:  Eur J Immunol       Date:  2012-01-18       Impact factor: 5.532

Review 2.  Pathogenesis of West Nile Virus infection: a balance between virulence, innate and adaptive immunity, and viral evasion.

Authors:  Melanie A Samuel; Michael S Diamond
Journal:  J Virol       Date:  2006-10       Impact factor: 5.103

3.  Interleukin-17A Promotes CD8+ T Cell Cytotoxicity To Facilitate West Nile Virus Clearance.

Authors:  Dhiraj Acharya; Penghua Wang; Amber M Paul; Jianfeng Dai; David Gate; Jordan E Lowery; Dobrivoje S Stokic; A Arturo Leis; Richard A Flavell; Terrence Town; Erol Fikrig; Fengwei Bai
Journal:  J Virol       Date:  2016-12-16       Impact factor: 5.103

4.  Dendritic cells in cancer immunotherapy: vaccines or autologous transplants?

Authors:  Pawel Kalinski; Howard Edington; Herbert J Zeh; Hideho Okada; Lisa H Butterfield; John M Kirkwood; David L Bartlett
Journal:  Immunol Res       Date:  2011-08       Impact factor: 2.829

5.  Indirect regulation of CD4 T-cell responses by tumor necrosis factor receptors in an acute viral infection.

Authors:  Anju Singh; Marcel Wüthrich; Bruce Klein; M Suresh
Journal:  J Virol       Date:  2007-04-04       Impact factor: 5.103

Review 6.  Innate and adaptive immune responses to Listeria monocytogenes: a short overview.

Authors:  Lauren A Zenewicz; Hao Shen
Journal:  Microbes Infect       Date:  2007-05-07       Impact factor: 2.700

7.  Mycobacterium tuberculosis-specific CD8+ T cells require perforin to kill target cells and provide protection in vivo.

Authors:  Joshua S Woodworth; Ying Wu; Samuel M Behar
Journal:  J Immunol       Date:  2008-12-15       Impact factor: 5.422

8.  Antigen-driven effector CD8 T cell function regulated by T-bet.

Authors:  Brandon M Sullivan; Amy Juedes; Susanne J Szabo; Matthias von Herrath; Laurie H Glimcher
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-12       Impact factor: 11.205

9.  CD8 T cells use IFN-γ to protect against the lethal effects of a respiratory poxvirus infection.

Authors:  John Goulding; Georges Abboud; Vikas Tahiliani; Pritesh Desai; Tarun E Hutchinson; Shahram Salek-Ardakani
Journal:  J Immunol       Date:  2014-04-18       Impact factor: 5.422

10.  The early kinetics of cytomegalovirus-specific CD8+ T-cell responses are not affected by antigen load or the absence of perforin or gamma interferon.

Authors:  Daniel M Andrews; Christopher E Andoniou; Peter Fleming; Mark J Smyth; Mariapia A Degli-Esposti
Journal:  J Virol       Date:  2008-03-12       Impact factor: 5.103

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