Literature DB >> 11972105

Interaction between methotrexate and ciprofloxacin.

Jean-Hugues Dalle1, Anne Auvrignon, Gilles Vassal, Guy Leverger.   

Abstract

High-dose methotrexate is used in malignant hemopathies and solid tumors in children. Methotrexate serum concentrations must be monitored because of the possible toxicity of drug elimination delay. Several drugs (e.g., penicillin, probenecid) can alter the elimination of methotrexate. The authors report two cases of delayed elimination of methotrexate in patients receiving ciprofloxacin, with severe toxicity.

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Year:  2002        PMID： 11972105     DOI： 10.1097/00043426-200205000-00021

Source DB:  PubMed          Journal:  J Pediatr Hematol Oncol        ISSN： 1077-4114            Impact factor:   1.289


  9 in total

1.  Acute kidney injury, agranulocytosis, drug-induced liver injury, and posterior reversible encephalopathy syndrome caused by high-dose methotrexate-possible role of low activity ABC and SLC drug transporters.

Authors:  L Bielen; I Kralj; Ela Ćurčić; M Vodanović; A Boban; N Božina
Journal:  Eur J Clin Pharmacol       Date:  2018-05-22       Impact factor: 2.953

Review 2.  Renal Drug Transporters and Drug Interactions.

Authors:  Anton Ivanyuk; Françoise Livio; Jérôme Biollaz; Thierry Buclin
Journal:  Clin Pharmacokinet       Date:  2017-08       Impact factor: 6.447

3.  High incidence of methotrexate associated renal toxicity in patients with lymphoma: a retrospective analysis.

Authors:  Jori May; Kenneth R Carson; Sara Butler; Weijian Liu; Nancy L Bartlett; Nina D Wagner-Johnston
Journal:  Leuk Lymphoma       Date:  2013-11-01

4.  Inhibitory Interaction Potential of 22 Antituberculosis Drugs on Organic Anion and Cation Transporters of the SLC22A Family.

Authors:  M Masud Parvez; Nazia Kaisar; Ho Jung Shin; Jin Ah Jung; Jae-Gook Shin
Journal:  Antimicrob Agents Chemother       Date:  2016-10-21       Impact factor: 5.191

5.  Effect of ciprofloxacin and ibuprofen on the in vitro metabolism of rosiglitazone and oral pharmacokinetics of rosiglitazone in healthy human volunteers.

Authors:  J N Suresh Kumar; Prameela Devi; Lakshmi Narasu; Ramesh Mullangi
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2008 Oct-Dec       Impact factor: 2.441

Review 6.  Ciprofloxacin safety in paediatrics: a systematic review.

Authors:  Abiodun Adefurin; Helen Sammons; Evelyne Jacqz-Aigrain; Imti Choonara
Journal:  Arch Dis Child       Date:  2011-07-23       Impact factor: 3.791

7.  Atypical methotrexate ulcerative stomatitis with features of lymphoproliferative like disorder: Report of a rare ciprofloxacin-induced case and review of the literature.

Authors:  Nikolaos Katsoulas; Evanthia Chrysomali; Evangelia Piperi; Georgia Levidou; Alexandra Sklavounou-Andrikopoulou
Journal:  J Clin Exp Dent       Date:  2016-12-01

8.  Ceftazidime and cefepime antagonize 5-fluorouracil's effect in colon cancer cells.

Authors:  Christina Pfab; Anush Abgaryan; Barbara Danzer; Fatme Mourtada; Weaam Ali; André Gessner; Nahed El-Najjar
Journal:  BMC Cancer       Date:  2022-01-31       Impact factor: 4.430

9.  Methotrexate Decreases Tenofovir Exposure in Antiretroviral-Suppressed Individuals Living With HIV.

Authors:  David Gingrich; Amelia N Deitchman; Amy Kantor; Liusheng Huang; James H Stein; Judith S Currier; Priscilla Y Hsue; Heather J Ribaudo; Francesca T Aweeka
Journal:  J Acquir Immune Defic Syndr       Date:  2020-12-15       Impact factor: 3.771
  9 in total

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