| Literature DB >> 1197141 |
J W Constantine, W K McShane, A Scriabine, H J Hess.
Abstract
Results of animal studies indicate that the hypotensive effect of prazosin is due to vasodilatation which is dependent on two discernible components of drug action: (1) direct relaxation of vascular smooth muscle and (2) interference with peripheral sympathetic function at a site distal to the alpha-adrenergic receptor.Entities:
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Year: 1975 PMID： 1197141
Source DB: PubMed Journal: Postgrad Med ISSN： 0032-5481 Impact factor: 3.840