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Literature DB >> 11970888

Signal transduction in development: holding the key.

Abstract

The unrelated GSK-3 and CK1 families stand out among the protein kinases because of their phosphorylated substrate recognition sites. Two papers in the March 22nd issue of Cell highlight the importance of this priming phosphorylation for signal transduction during development.

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Year: 2002 PMID： 11970888 DOI： 10.1016/s1534-5807(02)00156-9

Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270

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Cited

9 in total

1. From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity.

Authors: Emilie Durieu; Eric Prina; Olivier Leclercq; Nassima Oumata; Nicolas Gaboriaud-Kolar; Konstantina Vougogiannopoulou; Nathalie Aulner; Audrey Defontaine; Joo Hwan No; Sandrine Ruchaud; Alexios-Leandros Skaltsounis; Hervé Galons; Gerald F Späth; Laurent Meijer; Najma Rachidi
Journal: Antimicrob Agents Chemother Date: 2016-04-22 Impact factor: 5.191

2. Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3.

Authors: Jae Hyung An; Kelly Vranas; Michael Lucke; Hideki Inoue; Naoki Hisamoto; Kunihiro Matsumoto; T Keith Blackwell
Journal: Proc Natl Acad Sci U S A Date: 2005-10-26 Impact factor: 11.205

3. Functional studies of shaggy/glycogen synthase kinase 3 phosphorylation sites in Drosophila melanogaster.

Authors: Deppie Papadopoulou; Michele Wolfe Bianchi; Marc Bourouis
Journal: Mol Cell Biol Date: 2004-06 Impact factor: 4.272

4. p190A RhoGAP is a glycogen synthase kinase-3-beta substrate required for polarized cell migration.

Authors: Wei Jiang; Martha Betson; Roseann Mulloy; Rosemary Foster; Magdolna Lévay; Erzsébet Ligeti; Jeffrey Settleman
Journal: J Biol Chem Date: 2008-05-23 Impact factor: 5.157

5. IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508.

Authors: Eun Sook Hwang; Jeong-Ho Hong; Laurie H Glimcher
Journal: J Exp Med Date: 2005-11-07 Impact factor: 14.307

Signal transduction in development: holding the key.

1. From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity.

2. Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3.

3. Functional studies of shaggy/glycogen synthase kinase 3 phosphorylation sites in Drosophila melanogaster.

4. p190A RhoGAP is a glycogen synthase kinase-3-beta substrate required for polarized cell migration.

5. IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508.

Review 6. Casein kinase 1α: biological mechanisms and theranostic potential.

7. Mitotic HOOK3 phosphorylation by ERK1c drives microtubule-dependent Golgi destabilization and fragmentation.

8. A chemical genomic study identifying diversity in cell migration signaling in cancer cells.

9. Protein kinase substrate identification on functional protein arrays.