Literature DB >> 119705

Plaque forming cell assay to measure responses in mice to the random copolymer (Glu60Phe40).

U M Babu, P H Maurer, C F Merryman, J M Anderson.   

Abstract

A plaque-forming cell (PFC) assay to measure the immune response of mice to the synthetic random copolymer of glutamic acid and phenylalanine (GPhe) is described here. GPhe can be coupled to sheep red blood cells (SRBC) using "aged" CrCl3. Both IgM and IgG plaques are detected in the murine GPhe response. Mice of H-2 haploytpes p and q are high responders, a and k are medium or low responders and b, d and s are nonresponders as detected by the PFC assay.

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Year:  1979        PMID: 119705     DOI: 10.3109/08820137909063251

Source DB:  PubMed          Journal:  Immunol Commun        ISSN: 0090-0877


  3 in total

1.  Ir gene control of T and B cell responses to determinants in poly(Glu, Ala, Phe).

Authors:  U M Babu; C H Lai; P H Maurer
Journal:  Immunogenetics       Date:  1983       Impact factor: 2.846

2.  Reevaluation of response patterns of nonresponder mice to GLPhe polymers.

Authors:  U M Babu; C Hai-Lai; P H Maurer
Journal:  Immunogenetics       Date:  1983       Impact factor: 2.846

3.  The expression of anti-poly(LGlu60, LPhe40) idiotypic determinants dictated by the gene products in the major histocompatibility complex.

Authors:  U M Babu; P H Maurer
Journal:  J Exp Med       Date:  1981-09-01       Impact factor: 14.307

  3 in total

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