Literature DB >> 11968497

Targeting random mutations to hotspots in antibody variable domains for affinity improvement.

Partha S Chowdhury.   

Abstract

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Year:  2002        PMID： 11968497     DOI： 10.1385/1-59259-240-6:269

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


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  2 in total

1.  A general method for greatly improving the affinity of antibodies by using combinatorial libraries.

Authors:  Arvind Rajpal; Nurten Beyaz; Lauric Haber; Guido Cappuccilli; Helena Yee; Ramesh R Bhatt; Toshihiko Takeuchi; Richard A Lerner; Roberto Crea
Journal:  Proc Natl Acad Sci U S A       Date:  2005-06-06       Impact factor: 11.205

2.  Affinity maturation of a portable Fab-RNA module for chaperone-assisted RNA crystallography.

Authors:  Deepak Koirala; Sandip A Shelke; Marcel Dupont; Stormy Ruiz; Saurja DasGupta; Lucas J Bailey; Steven A Benner; Joseph A Piccirilli
Journal:  Nucleic Acids Res       Date:  2018-03-16       Impact factor: 16.971
  2 in total

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