Literature DB >> 11967344

Expression of a membrane-anchored glycoprotein, the influenza virus hemagglutinin, by dicistronic replicons derived from the poliovirus genome.

Marco Vignuzzi1, Sylvie Gerbaud, Sylvie van der Werf, Nicolas Escriou.   

Abstract

Mono- and dicistronic poliovirus replicons were constructed to express the influenza virus hemagglutinin, retaining its signal peptide and transmembrane region. Picornavirus genomes do not normally encode glycoproteins, and only the dicistronic replicon, in which the foreign and poliovirus sequences were separated by the encephalomyocarditis virus internal ribosomal entry site, replicated and expressed glycosylated hemagglutinin.

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Year:  2002        PMID： 11967344      PMCID： PMC136135          DOI： 10.1128/jvi.76.10.5285-5290.2002

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  16 in total

1.  A poliovirus replicon containing the chloramphenicol acetyltransferase gene can be used to study the replication and encapsidation of poliovirus RNA.

Authors:  N Percy; W S Barclay; M Sullivan; J W Almond
Journal:  J Virol       Date:  1992-08       Impact factor: 5.103

2.  Characterization of poliovirus replicons encoding carcinoembryonic antigen.

Authors:  D C Ansardi; Z Moldoveanu; D C Porter; D E Walker; R M Conry; A F LoBuglio; S McPherson; C D Morrow
Journal:  Cancer Res       Date:  1994-12-15       Impact factor: 12.701

3.  Naked RNA immunization with replicons derived from poliovirus and Semliki Forest virus genomes for the generation of a cytotoxic T cell response against the influenza A virus nucleoprotein.

Authors:  Marco Vignuzzi; Sylvie Gerbaud; Sylvie van der Werf; Nicolas Escriou
Journal:  J Gen Virol       Date:  2001-07       Impact factor: 3.891

4.  Inhibition of endoplasmic reticulum-to-Golgi traffic by poliovirus protein 3A: genetic and ultrastructural analysis.

Authors:  J R Doedens; T H Giddings; K Kirkegaard
Journal:  J Virol       Date:  1997-12       Impact factor: 5.103

5.  Construction and genetic analysis of dicistronic polioviruses containing open reading frames for epitopes of human immunodeficiency virus type 1 gp120.

Authors:  H H Lu; L Alexander; E Wimmer
Journal:  J Virol       Date:  1995-08       Impact factor: 5.103

6.  Encapsidation of poliovirus replicons encoding the complete human immunodeficiency virus type 1 gag gene by using a complementation system which provides the P1 capsid protein in trans.

Authors:  D C Porter; D C Ansardi; C D Morrow
Journal:  J Virol       Date:  1995-03       Impact factor: 5.103

7.  Expression of human immunodeficiency virus type 1 (HIV-1) gag, pol, and env proteins from chimeric HIV-1-poliovirus minireplicons.

Authors:  W S Choi; R Pal-Ghosh; C D Morrow
Journal:  J Virol       Date:  1991-06       Impact factor: 5.103

8.  The sequence context of the initiation codon in the encephalomyocarditis virus leader modulates efficiency of internal translation initiation.

Authors:  M V Davies; R J Kaufman
Journal:  J Virol       Date:  1992-04       Impact factor: 5.103

9.  Role of myristoylation of poliovirus capsid protein VP4 as determined by site-directed mutagenesis of its N-terminal sequence.

Authors:  D Marc; G Drugeon; A L Haenni; M Girard; S van der Werf
Journal:  EMBO J       Date:  1989-09       Impact factor: 11.598

10.  Inhibition of cellular protein secretion by poliovirus proteins 2B and 3A.

Authors:  J R Doedens; K Kirkegaard
Journal:  EMBO J       Date:  1995-03-01       Impact factor: 11.598
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  2 in total

1.  Sindbis virus vectors designed to express a foreign protein as a cleavable component of the viral structural polyprotein.

Authors:  John M Thomas; William B Klimstra; Kate D Ryman; Hans W Heidner
Journal:  J Virol       Date:  2003-05       Impact factor: 5.103

2.  RNA replicons - a new approach for influenza virus immunoprophylaxis.

Authors:  Gert Zimmer
Journal:  Viruses       Date:  2010-01-29       Impact factor: 5.818
  2 in total

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