| Literature DB >> 11965427 |
Luiz Felipe Rocha Vasconcellos1, Rosalie Branco Correa, Leila Chimelli, Fernanda Nascimento, Adriane Baptista Fonseca, Janaina Nagel, Sergio Augusto Pereira Novis, Maurice Vincent.
Abstract
Vitamin B12 deficiency may induce neuropathy, myelopathy, dementia and optic neuropathy. The diagnosis is established by vitamin B12, homocysteine and methylmalonic acid measurements. Myelin and axon destruction in the white matter of the spinal cord are observed. The posterior column of the cervical and thoracic level is the most common involved area. The involvement of the anterior column is restricted to advanced and relatively severe cases. Treatment is based on vitamin B12 injections, and the prognosis depends on the stage of vitamin deficiency and deterioration at treatment onset. We report a case with transverse myelitis due to vitamin B12 deficiency. This picture is relatively uncommon, however, we believe patients with transverse myelitis should have vitamin B12 studies as part of the diagnosis work up.Entities:
Mesh:
Year: 2002 PMID: 11965427 DOI: 10.1590/s0004-282x2002000100028
Source DB: PubMed Journal: Arq Neuropsiquiatr ISSN: 0004-282X Impact factor: 1.420