OBJECTIVE: This study aims to show preliminary results of the 'combined treatment' (acetylcholinesterase inhibitor + cognitive training) on a group of mild Alzheimer's disease (AD) patients, followed-up for 7 months. METHODS:Six mild AD patients, diagnosed according to ICD-10 and NINCDS-ADRDA criteria, were included on a open trial with Rivastigmine, 6-12 mg/day, for 2 months, followed by a weekly cognitive rehabilitation group, for 5 months. Caregivers were submitted to a weekly group of counseling and support for 5 months. RESULTS: Stabilization or mild improvement of patients' cognitive and activities of daily living deficits were found, besides reduction of patients and caregivers' depressive and anxiety levels. CONCLUSION: The 'combined treatment' can help on the stabilization or result on a mild improvement of AD patients' cognitive and functional deficits. Support and counseling interventions can reduce the levels of caregivers' psychiatric symptoms.
RCT Entities:
OBJECTIVE: This study aims to show preliminary results of the 'combined treatment' (acetylcholinesterase inhibitor + cognitive training) on a group of mild Alzheimer's disease (AD) patients, followed-up for 7 months. METHODS: Six mild ADpatients, diagnosed according to ICD-10 and NINCDS-ADRDA criteria, were included on a open trial with Rivastigmine, 6-12 mg/day, for 2 months, followed by a weekly cognitive rehabilitation group, for 5 months. Caregivers were submitted to a weekly group of counseling and support for 5 months. RESULTS: Stabilization or mild improvement of patients' cognitive and activities of daily living deficits were found, besides reduction of patients and caregivers' depressive and anxiety levels. CONCLUSION: The 'combined treatment' can help on the stabilization or result on a mild improvement of ADpatients' cognitive and functional deficits. Support and counseling interventions can reduce the levels of caregivers' psychiatric symptoms.
Authors: Luciane F Viola; Paula V Nunes; Monica S Yassuda; Ivan Aprahamian; Franklin S Santos; Glenda D Santos; Paula S Brum; Sheila M Borges; Alexandra M Oliveira; Gisele F S Chaves; Eliane C Ciasca; Rita C R Ferreira; Vanessa J R de Paula; Oswaldo H Takeda; Roberta M Mirandez; Ricky Watari; Deusivania V S Falcao; Meire Cachioni; Orestes V Forlenza Journal: Clinics (Sao Paulo) Date: 2011 Impact factor: 2.365
Authors: Fernanda Machado; Paula V Nunes; Luciane F Viola; Franklin S Santos; Orestes V Forlenza; Mônica S Yassuda Journal: Dement Neuropsychol Date: 2009 Jul-Sep
Authors: Carolina P M Pereira; Florindo Stella; Salma S S Hernandez; Larissa P Andrade; Camila V L Texeira; Sebastião Gobbi Journal: Dement Neuropsychol Date: 2010 Jul-Sep