Literature DB >> 11965371

Synthesis of a novel fluorescent probe for estrogen receptor.

Maciej Adamczyk1, Rajarathnam E Reddy, Zhiguang Yu.   

Abstract

A novel estradiol-mimetic fluorescent probe 5 was synthesized from diethylstilbestrol (DES, 1), which is useful for probing estrogen receptor (ERalpha), a prognostic indicator of estrogen-dependent cancers, and for developing a homogeneous fluorescence polarization (FP) assay to identify the ligands of estrogen receptor.

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Year:  2002        PMID： 11965371     DOI： 10.1016/s0960-894x(02)00144-0

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  2 in total

1.  Differential recruitment of co-regulatory proteins to the human estrogen receptor 1 in response to xenoestrogens.

Authors:  L Cody Smith; Jessica C Clark; Joseph H Bisesi; P Lee Ferguson; Tara Sabo-Attwood
Journal:  Comp Biochem Physiol Part D Genomics Proteomics       Date:  2016-04-20       Impact factor: 2.674

2.  Fluorescent ligand for human progesterone receptor imaging in live cells.

Authors:  Roy Weinstain; Joan Kanter; Beth Friedman; Lesley G Ellies; Michael E Baker; Roger Y Tsien
Journal:  Bioconjug Chem       Date:  2013-04-29       Impact factor: 4.774
  2 in total

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