Literature DB >> 11964776

Buruli ulcer.

Mark R.W. Evans1, Harry S. Thangaraj, Mark H. Wansbrough-Jones.   

Abstract

Buruli ulcer (Mycobacterium ulcerans) is an emerging disease. The mode of transmission is still unknown. Mycobacterium ulcerans has been detected (by polymerase chain reaction) in water and water insects. Extensive surgery is still the main treatment. Recognition and excision - of the early nodular stage - is effective. The toxin, a polyketide, causes immunosuppression with potent inhibition of monocytes, T cells and nuclear factor kappa-B activation.

Entities:  

Year:  2000        PMID： 11964776     DOI： 10.1097/00001432-200004000-00003

Source DB:  PubMed          Journal:  Curr Opin Infect Dis        ISSN： 0951-7375            Impact factor:   4.915


  6 in total

1.  Infection with Mycobacterium ulcerans induces persistent inflammatory responses in mice.

Authors:  Martinha S Oliveira; Alexandra G Fraga; Egídio Torrado; António G Castro; João P Pereira; Adhemar Longatto Filho; Fernanda Milanezi; Fernando C Schmitt; Wayne M Meyers; Françoise Portaels; Manuel T Silva; Jorge Pedrosa
Journal:  Infect Immun       Date:  2005-10       Impact factor: 3.441

2.  Evidence for an intramacrophage growth phase of Mycobacterium ulcerans.

Authors:  Egídio Torrado; Alexandra G Fraga; António G Castro; Pieter Stragier; Wayne M Meyers; Françoise Portaels; Manuel T Silva; Jorge Pedrosa
Journal:  Infect Immun       Date:  2006-12-04       Impact factor: 3.441

3.  Mycolactone-mediated inhibition of tumor necrosis factor production by macrophages infected with Mycobacterium ulcerans has implications for the control of infection.

Authors:  Egídio Torrado; Sarojini Adusumilli; Alexandra G Fraga; Pamela L C Small; António G Castro; Jorge Pedrosa
Journal:  Infect Immun       Date:  2007-05-21       Impact factor: 3.441

4.  Secondary Buruli ulcer skin lesions emerging several months after completion of chemotherapy: paradoxical reaction or evidence for immune protection?

Authors:  Marie-Thérèse Ruf; Annick Chauty; Ambroise Adeye; Marie-Françoise Ardant; Hugues Koussemou; Roch Christian Johnson; Gerd Pluschke
Journal:  PLoS Negl Trop Dis       Date:  2011-08-02

5.  Chronic wounds in Sierra Leone: Searching for Buruli ulcer, a NTD caused by Mycobacterium ulcerans, at Masanga Hospital.

Authors:  Helen R Please; Jonathan H Vas Nunes; Rashida Patel; Gerd Pluschke; Mohamed Tholley; Marie-Therésè Ruf; William Bolton; Julian A Scott; Martin P Grobusch; Håkon A Bolkan; Julia M Brown; David G Jayne
Journal:  PLoS Negl Trop Dis       Date:  2021-10-13

6.  Mycolactone diffuses from Mycobacterium ulcerans-infected tissues and targets mononuclear cells in peripheral blood and lymphoid organs.

Authors:  Hui Hong; Emmanuelle Coutanceau; Marion Leclerc; Laxmee Caleechurn; Peter F Leadlay; Caroline Demangel
Journal:  PLoS Negl Trop Dis       Date:  2008-10-22
  6 in total

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