Daniel E Goldberg1. Show Affiliations » 1. Howard Hughes Medical Institute, Department of Medicine and Department of Molecular Microbiology, Washington University, St. Louis, MO 63130, USA. goldberg@borcim.wustl.edu
Abstract
Mesh： See more » AnimalsAntimalarials/pharmacologyDatabases, Nucleic AcidDown-RegulationDrug Evaluation, PreclinicalErythrocytes/parasitologyFolic Acid/metabolismFolic Acid Antagonists/pharmacologyGenes, ProtozoanGenome, ProtozoanHost-Parasite InteractionsHumansMultienzyme Complexes/geneticsMultienzyme Complexes/metabolismPlasmodium falciparum/drug effectsPlasmodium falciparum/enzymologyPlasmodium falciparum/geneticsProtein BiosynthesisProteomeProtozoan Proteins/geneticsProtozoan Proteins/metabolismRNA, Messenger/geneticsRNA, Messenger/metabolismRNA, Protozoan/geneticsRNA, Protozoan/metabolismTetrahydrofolate Dehydrogenase/geneticsTetrahydrofolate Dehydrogenase/metabolismThymidylate Synthase/geneticsThymidylate Synthase/metabolismUp-Regulation
Substances： See more » AntimalarialsFolic Acid AntagonistsMultienzyme ComplexesProteomeProtozoan ProteinsRNA, MessengerRNA, Protozoanthymidylate synthase-dihydrofolate reductaseFolic AcidTetrahydrofolate DehydrogenaseThymidylate Synthase
Year: 2002 PMID： 11964467 DOI： 10.1126/science.1071206
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728