OBJECTIVE: To evaluate serum lipids in children with type 1 diabetes mellitus and its relation to glycemic control, in comparison with matched controls. SETTING: Basrah Maternity and Children Hospital, Basrah, Iraq. METHOD: Lipid profile was studied in 32 children (17 males and 15 females) with type 1 diabetes mellitus from October 1999 to September 2000. Seventy seven non-diabetic children (35 males and 42 females) admitted with acute illness in the same hospital were selected as controls. RESULTS: The age and BMI was similar in both groups. The mean total cholesterol, triglycerides, HDL-C, LDL-C, VLDL-C and LDL-C/HDL-C ratio were significantly higher in diabetic children compared to control group. There was no significant difference in the levels of Apo O and Apo B in both groups. CONCLUSION: Children with type 1 diabetes should be screened for serum lipids as significant lipid abnormalities are related to glycemic control. Both can be improved with dietary management and insulin therapy.
OBJECTIVE: To evaluate serum lipids in children with type 1 diabetes mellitus and its relation to glycemic control, in comparison with matched controls. SETTING: Basrah Maternity and Children Hospital, Basrah, Iraq. METHOD:Lipid profile was studied in 32 children (17 males and 15 females) with type 1 diabetes mellitus from October 1999 to September 2000. Seventy seven non-diabeticchildren (35 males and 42 females) admitted with acute illness in the same hospital were selected as controls. RESULTS: The age and BMI was similar in both groups. The mean total cholesterol, triglycerides, HDL-C, LDL-C, VLDL-C and LDL-C/HDL-C ratio were significantly higher in diabeticchildren compared to control group. There was no significant difference in the levels of Apo O and Apo B in both groups. CONCLUSION:Children with type 1 diabetes should be screened for serum lipids as significant lipid abnormalities are related to glycemic control. Both can be improved with dietary management and insulin therapy.
Authors: Soha M Abd El Dayem; Mona Abd El Kader; Soheir Ibrahim; Enas Mokhtar; Eman Abd El Megeed Journal: Open Access Maced J Med Sci Date: 2017-03-19