Literature DB >> 1196299

Cycloheximide resistance in Chinese hamster cells. III. Characterization of cell-free protein synthesis by polysomes.

H Pöche, I Junghahn, E Geissler, H Bielka.   

Abstract

Two clones were selected for mass cultivation from 18 phenotypically stable CHM-resistant CHO clones. The polysomes isolated from these two clones were compared with CHO wildtype polysomes and rat liver polysomes in a cell-free protein synthesis system for their ability to incorporate amino acids. CHM had an inhibitory effect on the protein synthesis activity of CHO wildtype and rat liver polysomes, but had no effect on the polysomes obtained from either of the mutant CHO clones.

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Year:  1975        PMID： 1196299

Source DB:  PubMed          Journal:  Mol Gen Genet        ISSN： 0026-8925


  9 in total

1.  Cycloheximide resistance in carrot culture.

Authors:  P M Gresshoff
Journal:  Theor Appl Genet       Date:  1979-05       Impact factor: 5.699

2.  Resistance against cycloheximide in cell lines from Chinese hamster and human cells is conferred by the large subunit of cytoplasmic ribosomes.

Authors:  H Pöche; S Zakrzewski; K H Nierhaus
Journal:  Mol Gen Genet       Date:  1979-09

3.  Isolation and characterization of a cycloheximide-resistant mutant of Acanthamoeba castellanii Neff.

Authors:  G E Chisholm; M H Vaughan
Journal:  J Bacteriol       Date:  1979-04       Impact factor: 3.490

4.  Transient cycloheximide resistance in a tobacco cell line.

Authors:  P Maliga; G Lázár; Z Sváb; F Nagy
Journal:  Mol Gen Genet       Date:  1976-12-22

5.  Cycloheximide-resistance in Chinese hamster ovary cells and human fibroblast cells. Cytogenetic and biochemical characterization.

Authors:  H Pöche; K H Nierhaus; S Zakrzewski
Journal:  Hum Genet       Date:  1979-09       Impact factor: 4.132

6.  Cycloheximide resistance can be mediated through either ribosomal subunit.

Authors:  C A Sutton; M Ares; R L Hallberg
Journal:  Proc Natl Acad Sci U S A       Date:  1978-07       Impact factor: 11.205

7.  Binding of cycloheximide to ribosomes from wild-type and mutant strains of Saccharomyces cerevisiae.

Authors:  W Stöcklein; W Piepersberg
Journal:  Antimicrob Agents Chemother       Date:  1980-12       Impact factor: 5.191

8.  Nucleotide sequences required for the regulation of a rat alpha 2u-globulin gene by glucocorticoids.

Authors:  W R Addison; D T Kurtz
Journal:  Mol Cell Biol       Date:  1986-07       Impact factor: 4.272

9.  Altered ribosomal protein L29 in a cycloheximide-resistant strain of Saccharomyces cerevisiae.

Authors:  W Stöcklein; W Piepersberg
Journal:  Curr Genet       Date:  1980-04       Impact factor: 3.886
  9 in total

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