| Literature DB >> 11960701 |
Ali S Morsi El-Kadi1, Paul in der Reiden, Antony Durston, Richard Morgan.
Abstract
The Hox genes are a family of homeodomain-containing transcription factors which determine anteroposterior identity early on in development. Although a lot is now known about their regulation and function, very little is known of their effector (downstream target) genes. Here we show that the small GTPase Rap1 is a direct, negatively regulated target of Hoxb4 and is excluded from Hoxb4 expressing cells.Entities:
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Year: 2002 PMID： 11960701 DOI： 10.1016/s0925-4773(02)00047-3
Source DB: PubMed Journal: Mech Dev ISSN： 0925-4773 Impact factor: 1.882