| Literature DB >> 11959598 |
Silke C Mueller1, Jolanta Majcher-Peszynska, Heiko Hickstein, Astrid Francke, Annette Pertschy, Martin Schulz, Ralf Mundkowski, Bernd Drewelow.
Abstract
The pharmacokinetics of piperacillin-tazobactam were investigated in eight anuric intensive care patients treated by continuous venovenous hemodialysis (CVVHD). The elimination half-life of piperacillin was 4.3 +/- 1.2 h, and that of tazobactam was 5.6 +/- 1.3 h. The contribution of CVVHD to the overall elimination was relevant (>25%) for both drugs.Entities:
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Year: 2002 PMID: 11959598 PMCID: PMC127124 DOI: 10.1128/AAC.46.5.1557-1560.2002
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191