| Literature DB >> 11959555 |
A Carattoli1, F Tosini, W P Giles, M E Rupp, S H Hinrichs, F J Angulo, T J Barrett, P D Fey.
Abstract
Sequencing of DNA from 15 expanded-spectrum cephalosporin (e.g., ceftriaxone)-resistant Salmonella isolates obtained in the United States revealed that resistance to ceftriaxone in all isolates was mediated by cmy-2. Hybridization patterns revealed three plasmid structures containing cmy-2 in these 15 isolates. These data suggest that the spread of cmy-2 among Salmonella strains is occurring through mobilization of the cmy-2 gene into different plasmid backbones and consequent horizontal transfer by conjugation.Entities:
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Year: 2002 PMID: 11959555 PMCID: PMC127137 DOI: 10.1128/AAC.46.5.1269-1272.2002
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191