| Literature DB >> 11959007 |
Frédéric Alvarez1, Arnaud Ghérardi, Pascal Nebois, Marie Elizabeth Sarciron, Anne Françoise Pétavy, Nadia Walchshofer.
Abstract
Benzimidazole-4,7-diones derivatives substituted at 1- and/or 2-position have been synthetized and tested as inhibitors of purine nucleoside phosphorylase (PNP), isolated from two strains of Toxoplasma gondii (RH and ME 49). They were identified as inhibitors of both enzymes.Entities:
Mesh：
Substances：
Year: 2002 PMID： 11959007 DOI： 10.1016/s0960-894x(02)00064-1
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823