Literature DB >> 1195659

[Regan-isoenzyme of alkaline phosphatase in sera of cancer patients (author's transl)].

F G Lehmann.   

Abstract

The Regan-Isoenzyme of alkaline phosphatase was determined immunologically measuring the antibody-fixed tumor alkaline phosphatase activity. In 68 blood donors the normal range varied from 0.1145 to 0.6351 (delta E/20 min at 405 nm, chi = 0.3748, standard deviation = 0.1013). 28.9% of 83 patients with different carcinomas showed a pathologically elevated Regan-Isoenzyme activity in the serum. The percentage of positive results as compared to previous reports is higher due to a more sensitive technique.

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Year:  1975        PMID： 1195659     DOI： 10.1007/bf01468905

Source DB:  PubMed          Journal:  Klin Wochenschr        ISSN： 0023-2173


  12 in total

1.  A radioimmunoassay for placental-type alkaline phosphatase.

Authors:  B Jacoby; K D Bagshawe
Journal:  Cancer Res       Date:  1972-11       Impact factor: 12.701

2.  Biologically active water-insoluble protein polymers. I. Their use for isolation of antigens and antibodies.

Authors:  S Avrameas; T Ternynck
Journal:  J Biol Chem       Date:  1967-04-10       Impact factor: 5.157

3.  [Regan isoenzymes: isolation of alkaline phosphatase from the human placenta and development of a sensitive method for tumor diagnosis].

Authors:  F G Lehmann; D Lehmann
Journal:  Verh Dtsch Ges Inn Med       Date:  1974

4.  Ectopic production of an alkaline phosphatase isoenzyme in patients with cancer.

Authors:  L L Stolbach; M J Krant; W H Fishman
Journal:  N Engl J Med       Date:  1969-10-02       Impact factor: 91.245

5.  Increased incidence of placenta-like alkaline phosphatase activity in breast and genitourinary cancer.

Authors:  B J Cadeau; M E Blackstein; A Malkin
Journal:  Cancer Res       Date:  1974-04       Impact factor: 12.701

6.  A sensitive immunochemical method for the determination of the Regan isoenzyme in serum.

Authors:  M Usategui-Gomez; F M Yeager; A Fernandez de Castro
Journal:  Cancer Res       Date:  1973-07       Impact factor: 12.701

7.  New observations on the Regan isoenzyme of alkaline phosphatase in cancer patients.

Authors:  L Nathanson; W H Fishman
Journal:  Cancer       Date:  1971-06       Impact factor: 6.860

8.  Rapid electrophoretic microzone membrane technique for Regan isoenzyme (placental type alkaline phosphatase) usine a fluorogenic substrate.

Authors:  N R Inglis; D T Guzek; S Kirley; S Green; W H Fishman
Journal:  Clin Chim Acta       Date:  1971-07       Impact factor: 3.786

9.  A serum alkaline phosphatase isoenzyme of human neoplastic cell origin.

Authors:  W H Fishman; N I Inglis; L L Stolbach; M J Krant
Journal:  Cancer Res       Date:  1968-01       Impact factor: 12.701

10.  Glutamate dehydrogenase from human liver. III. Antibody-binding sites and properties of the antigen-antibody complex.

Authors:  F G Lehmann
Journal:  Biochim Biophys Acta       Date:  1971-05-12
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  1 in total

Review 1.  Serum-sialyltransferase activity in cancer patients.

Authors:  P G Berge; A Wilhelm; H Schriewer; G Wüst
Journal:  Klin Wochenschr       Date:  1982-05-03
  1 in total

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