Literature DB >> 11953417

Yersinia pseudotuberculosis produces a cytotoxic necrotizing factor.

Hank A Lockman1, Rebecca A Gillespie, Beth D Baker, Elizabeth Shakhnovich.   

Abstract

Cell extracts from Yersinia pseudotuberculosis induced multinucleation in HEp-2 cells in a manner similar to the effect caused by Escherichia coli cytotoxic necrotizing factor (CNF). The activity was not dependent on the Yersinia 70-kb virulence plasmid, and the activity was not inhibited by antibodies capable of neutralizing E. coli CNF type 1. The nucleotide sequence of the Yersinia cnf gene was 65.1% identical to the E. coli cnf gene.

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Year:  2002        PMID： 11953417      PMCID： PMC127951          DOI： 10.1128/IAI.70.5.2708-2714.2002

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  45 in total

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Journal:  Infect Immun       Date:  1991-12       Impact factor: 3.441

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Journal:  Infect Immun       Date:  1982-08       Impact factor: 3.441

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Journal:  Infect Immun       Date:  1983-03       Impact factor: 3.441
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  24 in total

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Authors:  H J Kadhum; D Finlay; M T Rowe; I G Wilson; H J Ball
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Review 3.  CNF1-like deamidase domains: common Lego bricks among cancer-promoting immunomodulatory bacterial virulence factors.

Authors:  Mengfei Ho; Amel Mettouchi; Brenda A Wilson; Emmanuel Lemichez
Journal:  Pathog Dis       Date:  2018-07-01       Impact factor: 3.166

4.  The cytotoxic necrotizing factors from Yersinia pseudotuberculosis and from Escherichia coli bind to different cellular receptors but take the same route to the cytosol.

Authors:  Britta Blumenthal; Claudia Hoffmann; Klaus Aktories; Steffen Backert; Gudula Schmidt
Journal:  Infect Immun       Date:  2007-04-16       Impact factor: 3.441

5.  Antibodies against hemolysin and cytotoxic necrotizing factor type 1 (CNF1) reduce bladder inflammation in a mouse model of urinary tract infection with toxigenic uropathogenic Escherichia coli.

Authors:  Mark A Smith; Rebecca A Weingarten; Lisa M Russo; Christy L Ventura; Alison D O'Brien
Journal:  Infect Immun       Date:  2015-02-09       Impact factor: 3.441

6.  Active cytotoxic necrotizing factor 1 associated with outer membrane vesicles from uropathogenic Escherichia coli.

Authors:  J Clavin Kouokam; Sun Nyunt Wai; Maria Fällman; Ulrich Dobrindt; Jörg Hacker; Bernt Eric Uhlin
Journal:  Infect Immun       Date:  2006-04       Impact factor: 3.441

7.  Cleavage of Escherichia coli cytotoxic necrotizing factor 1 is required for full biologic activity.

Authors:  Zeynep Knust; Britta Blumenthal; Klaus Aktories; Gudula Schmidt
Journal:  Infect Immun       Date:  2009-02-23       Impact factor: 3.441

8.  Cytotoxic necrotizing factor type 1-neutralizing monoclonal antibody NG8 recognizes three amino acids in a C-terminal region of the toxin and reduces toxin binding to HEp-2 cells.

Authors:  Kerian K Grande; Karen C Meysick; Susan B Rasmussen; Alison D O'Brien
Journal:  Infect Immun       Date:  2008-10-27       Impact factor: 3.441

9.  Cytotoxic necrotizing factor-Y boosts Yersinia effector translocation by activating Rac protein.

Authors:  Manuel Wolters; Erin C Boyle; Kerstin Lardong; Konrad Trülzsch; Anika Steffen; Klemens Rottner; Klaus Ruckdeschel; Martin Aepfelbacher
Journal:  J Biol Chem       Date:  2013-06-26       Impact factor: 5.157

Review 10.  Bacterial protein toxins that modify host regulatory GTPases.

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Journal:  Nat Rev Microbiol       Date:  2011-06-16       Impact factor: 60.633
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