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Literature DB >> 11953327

Novel targets for the control of secretory diarrhoea.

Abstract

Secretory diarrhoea continues to be a major clinical problem worldwide. It is now recognised that the enteric nervous system plays an important role in the pathogenesis of enterotoxin mediated intestinal secretion, which has resulted in the identification of novel therapeutic targets for the treatment of acute watery diarrhoea.

Entities: Disease

Mesh：

Substances：

Year: 2002 PMID： 11953327 PMCID： PMC1867674 DOI： 10.1136/gut.50.suppl_3.iii15

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

28 in total

1. Introduction. Enkephalinase inhibition: a rational approach to antisecretory therapy for acute diarrhoea.

Authors: M J Farthing
Journal: Aliment Pharmacol Ther Date: 1999-12 Impact factor: 8.171

2. Comparison of racecadotril and loperamide in children with acute diarrhoea.

Authors: D Turck; H Berard; N Fretault; J M Lecomte
Journal: Aliment Pharmacol Ther Date: 1999-12 Impact factor: 8.171

3. Racecadotril versus placebo in the treatment of acute diarrhoea in adults.

Authors: H Hamza; H Ben Khalifa; P Baumer; H Berard; J M Lecomte
Journal: Aliment Pharmacol Ther Date: 1999-12 Impact factor: 8.171

4. Efficacy and tolerability of racecadotril in acute diarrhea in children.

Authors: J P Cézard; J F Duhamel; M Meyer; I Pharaon; M Bellaiche; C Maurage; J L Ginies; J M Vaillant; J P Girardet; T Lamireau; A Poujol; A Morali; J Sarles; J P Olives; C Whately-Smith; S Audrain; J M Lecomte
Journal: Gastroenterology Date: 2001-03 Impact factor: 22.682

5. Neurokinin 1 and 2 receptors mediate cholera toxin secretion in rat jejunum.

Authors: J L Turvill; P Connor; M J Farthing
Journal: Gastroenterology Date: 2000-10 Impact factor: 22.682

6. The inhibition of cholera toxin-induced 5-HT release by the 5-HT(3) receptor antagonist, granisetron, in the rat.

Authors: J L Turvill; P Connor; M J Farthing
Journal: Br J Pharmacol Date: 2000-07 Impact factor: 8.739

7. Racecadotril in the treatment of acute watery diarrhea in children.

Authors: E Salazar-Lindo; J Santisteban-Ponce; E Chea-Woo; M Gutierrez
Journal: N Engl J Med Date: 2000-08-17 Impact factor: 91.245

8. Effect of vasoactive intestinal polypeptide (VIP) antagonism on rat jejunal fluid and electrolyte secretion induced by cholera and Escherichia coli enterotoxins.

Authors: F H Mourad; C F Nassar
Journal: Gut Date: 2000-09 Impact factor: 23.059

9. The sigma ligand, igmesine, inhibits cholera toxin and Escherichia coli enterotoxin induced jejunal secretion in the rat.

Authors: J L Turvill; P Kasapidis; M J Farthing
Journal: Gut Date: 1999-10 Impact factor: 23.059

10. Release of vasoactive intestinal polypeptide from the cat small intestine exposed to cholera toxin.

Authors: J Cassuto; J Fahrenkrug; M Jodal; R Tuttle; O Lundgren
Journal: Gut Date: 1981-11 Impact factor: 23.059

11 in total

Review 1. Management of infectious diarrhoea.

Authors: A C Casburn-Jones; M J G Farthing
Journal: Gut Date: 2004-02 Impact factor: 23.059

2. Antidiarrheal mechanism and ionic profile of Carpolobia lutea ethanolic stem-bark extract in rats.

Authors: Lucky Legbosi Nwidu; Orodje Onomor Ukiri; Clenilson Martins Rodrigues; Wagner Vilegas
Journal: Afr J Tradit Complement Altern Med Date: 2014-01-28

Review 3. Autonomic nervous system and secretion across the intestinal mucosal surface.

Authors: Jianjing Xue; Candice Askwith; Najma H Javed; Helen J Cooke
Journal: Auton Neurosci Date: 2007-03-02 Impact factor: 3.145

4. Chronic Diarrhea.

Authors: Lawrence R Schiller
Journal: Curr Treat Options Gastroenterol Date: 2005-06

5. Luminal Cholera Toxin Alters Motility in Isolated Guinea-Pig Jejunum via a Pathway Independent of 5-HT(3) Receptors.

Authors: Candice Fung; Melina Ellis; Joel C Bornstein
Journal: Front Neurosci Date: 2010-09-28 Impact factor: 4.677

6. A sexually dimorphic effect of cholera toxin: rapid changes in colonic motility mediated via a 5-HT3 receptor-dependent pathway in female C57Bl/6 mice.

Authors: Gayathri K Balasuriya; Elisa L Hill-Yardin; Michael D Gershon; Joel C Bornstein
Journal: J Physiol Date: 2016-05-12 Impact factor: 5.182

10. Both exogenous 5-HT and endogenous 5-HT, released by fluoxetine, enhance distension evoked propulsion in guinea-pig ileum in vitro.

Authors: Rachel M Gwynne; Amanda J Clarke; John B Furness; Joel C Bornstein
Journal: Front Neurosci Date: 2014-09-19 Impact factor: 4.677