| Literature DB >> 11951031 |
Ruslan Medzhitov1, Charles A Janeway.
Abstract
The innate immune system evolved several strategies of self/nonself discrimination that are based on the recognition of molecular patterns demarcating infectious nonself, as well as normal and abnormal self. These patterns are deciphered by receptors that either induce or inhibit an immune response, depending on the meaning of these signals.Mesh:
Substances:
Year: 2002 PMID: 11951031 DOI: 10.1126/science.1068883
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728