Alex C Wang1, Min-Chi Chen. 1. Department of Obstetrics and Gynaecology, Chang Gung University, Taoyuan, Taiwan.
Abstract
OBJECTIVE: To compare urethral pressure profilometry measurements using microtip transducer and double-lumen perfusion catheters. DESIGN: Prospective study. SETTING: Tertiary referral urogynaecology unit. SAMPLE: Three hundred and ninety two non-pregnant women with various lower urinary tract symptoms. METHODS: Multichannel urodynamic investigations were performed using double-lumen perfusion catheters with external pressure transducers in 392 women. For those 301 (76.8%) diagnosed as having genuine stress incontinence, an investigation with microtip transducers followed. For data analysis, a mixed-effects model was used to evaluate changes in the urethral profilometry and an approach proposed by Bland and Altman was applied to access agreement between the two techniques. RESULTS: Of the 301 women with genuine stress incontinence, 272 were eligible for this study. In resting status, the differences between the two techniques were statistically significant (48.9cm H2O vs 73.4cm H2O, P = 0.0001) after adjusting for age. Moreover, the agreement study also confirmed that these two techniques do not agree sufficiently. CONCLUSION: Maximum urethral closure pressure obtained from the double-lumen catheter was significantly higher than that obtained from the microtip catheter. Use of the double-lumen catheter for the measurement of maximum urethral closure pressure can be considered a reliable technique since its reproducibility is as good as that of the microtip catheter. Therefore, the diagnosis of 'low pressure urethra' will be different between the two techniques.
OBJECTIVE: To compare urethral pressure profilometry measurements using microtip transducer and double-lumen perfusion catheters. DESIGN: Prospective study. SETTING: Tertiary referral urogynaecology unit. SAMPLE: Three hundred and ninety two non-pregnant women with various lower urinary tract symptoms. METHODS: Multichannel urodynamic investigations were performed using double-lumen perfusion catheters with external pressure transducers in 392 women. For those 301 (76.8%) diagnosed as having genuine stress incontinence, an investigation with microtip transducers followed. For data analysis, a mixed-effects model was used to evaluate changes in the urethral profilometry and an approach proposed by Bland and Altman was applied to access agreement between the two techniques. RESULTS: Of the 301 women with genuine stress incontinence, 272 were eligible for this study. In resting status, the differences between the two techniques were statistically significant (48.9cm H2O vs 73.4cm H2O, P = 0.0001) after adjusting for age. Moreover, the agreement study also confirmed that these two techniques do not agree sufficiently. CONCLUSION: Maximum urethral closure pressure obtained from the double-lumen catheter was significantly higher than that obtained from the microtip catheter. Use of the double-lumen catheter for the measurement of maximum urethral closure pressure can be considered a reliable technique since its reproducibility is as good as that of the microtip catheter. Therefore, the diagnosis of 'low pressure urethra' will be different between the two techniques.
Authors: Andrew F Hundley; Morton B Brown; Linda Brubaker; Geoffrey W Cundiff; Karl Kreder; Peter Lotze; Holly E Richter; Halina Zyczynski; Anne M Weber; Anthony G Visco Journal: Int Urogynecol J Pelvic Floor Dysfunct Date: 2005-11-12
Authors: Charles W Nager; Larry Sirls; Heather J Litman; Holly Richter; Ingrid Nygaard; Toby Chai; Stephen Kraus; Halina Zyczynski; Kim Kenton; Liyuan Huang; John Kusek; Gary Lemack Journal: J Urol Date: 2011-06-16 Impact factor: 7.450
Authors: Charles W Nager; Stephen R Kraus; Kim Kenton; Larry Sirls; Toby C Chai; Clifford Wai; Gary Sutkin; Wendy Leng; Heather Litman; Liyuan Huang; Sharon Tennstedt; Holly E Richter Journal: Neurourol Urodyn Date: 2010-09 Impact factor: 2.696