Literature DB >> 11949952

Heritability and molecular genetic studies of endometriosis.

Joe Leigh Simpson1, Farideh Z Bischoff.   

Abstract

Endometriosis is well established as a condition showing heritable tendencies. Polygenic/multifactorial etiology appears far more likely to be the etiology than Mendelian inheritance. The current task is to determine the number and location of genes responsible for endometriosis. This paper shall review the basis for concluding that endometriosis is a genetic disorder of polygenic/multifactorial inheritance and outline selected strategies for identifying the number and location of causative genes. It shall also illustrate our approach to testing the hypothesis that endometriosis bears similarity to neoplasia and, hence, is a multistep phenomenon of clonal origin.

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Year:  2002        PMID： 11949952     DOI： 10.1111/j.1749-6632.2002.tb02785.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  22 in total

1.  High-density fine-mapping of a chromosome 10q26 linkage peak suggests association between endometriosis and variants close to CYP2C19.

Authors:  Jodie N Painter; Dale R Nyholt; Andrew Morris; Zhen Z Zhao; Anjali K Henders; Ann Lambert; Leanne Wallace; Nicholas G Martin; Stephen H Kennedy; Susan A Treloar; Krina T Zondervan; Grant W Montgomery
Journal:  Fertil Steril       Date:  2011-04-16       Impact factor: 7.329

Review 2.  The search for genes contributing to endometriosis risk.

Authors:  Grant W Montgomery; Dale R Nyholt; Zhen Zhen Zhao; Susan A Treloar; Jodie N Painter; Stacey A Missmer; Stephen H Kennedy; Krina T Zondervan
Journal:  Hum Reprod Update       Date:  2008-06-05       Impact factor: 15.610

3.  MicroRNA-142-3p suppresses endometriosis by regulating KLF9-mediated autophagy in vitro and in vivo.

Authors:  Lin Ma; Zaiyi Li; Weihao Li; Jing Ai; Xiaoxuan Chen
Journal:  RNA Biol       Date:  2019-08-25       Impact factor: 4.652

Review 4.  The dynamics of nuclear receptors and nuclear receptor coregulators in the pathogenesis of endometriosis.

Authors:  Sang Jun Han; Bert W O'Malley
Journal:  Hum Reprod Update       Date:  2014-03-14       Impact factor: 15.610

5.  Genomewide linkage study in 1,176 affected sister pair families identifies a significant susceptibility locus for endometriosis on chromosome 10q26.

Authors:  Susan A Treloar; Jacqueline Wicks; Dale R Nyholt; Grant W Montgomery; Melanie Bahlo; Vicki Smith; Gary Dawson; Ian J Mackay; Daniel E Weeks; Simon T Bennett; Alisoun Carey; Kelly R Ewen-White; David L Duffy; Daniel T O'connor; David H Barlow; Nicholas G Martin; Stephen H Kennedy
Journal:  Am J Hum Genet       Date:  2005-07-21       Impact factor: 11.025

6.  Common variation in the fibroblast growth factor receptor 2 gene is not associated with endometriosis risk.

Authors:  Zhen Zhen Zhao; Pamela M Pollock; Shane Thomas; Susan A Treloar; Dale R Nyholt; Grant W Montgomery
Journal:  Hum Reprod       Date:  2008-02-18       Impact factor: 6.918

7.  Do Estrogen Receptor beta Polymorphisms Play A Role in the Pharmacogenetics of Estrogen Signaling?

Authors:  Stephanie L Nott; Yanfang Huang; Brian R Fluharty; Anna M Sokolov; Melinda Huang; Cathleen Cox; Mesut Muyan
Journal:  Curr Pharmacogenomics Person Med       Date:  2008-12-01

Review 8.  An Evidence-Based Review of Elagolix for the Treatment of Pain Secondary to Endometriosis.

Authors:  Ivan Urits; Leena Adamian; Paulo Miro; Jessica Callan; Parth M Patel; Megha Patel; Amnon A Berger; Hisham Kassem; Alan D Kaye; Omar Viswanath
Journal:  Psychopharmacol Bull       Date:  2020-10-15

9.  Common variants in the CYP2C19 gene are associated with susceptibility to endometriosis.

Authors:  Jodie N Painter; Dale R Nyholt; Lutz Krause; Zhen Z Zhao; Brett Chapman; Christine Zhang; Sarah Medland; Nicholas G Martin; Stephen Kennedy; Susan Treloar; Krina Zondervan; Grant W Montgomery
Journal:  Fertil Steril       Date:  2014-05-03       Impact factor: 7.329

10.  Genome-wide association study identifies a locus at 7p15.2 associated with endometriosis.

Authors:  Jodie N Painter; Carl A Anderson; Dale R Nyholt; Stuart Macgregor; Jianghai Lin; Sang Hong Lee; Ann Lambert; Zhen Z Zhao; Fenella Roseman; Qun Guo; Scott D Gordon; Leanne Wallace; Anjali K Henders; Peter M Visscher; Peter Kraft; Nicholas G Martin; Andrew P Morris; Susan A Treloar; Stephen H Kennedy; Stacey A Missmer; Grant W Montgomery; Krina T Zondervan
Journal:  Nat Genet       Date:  2010-12-12       Impact factor: 38.330
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