BACKGROUND/AIMS: To compare the diagnostic accuracy of an immunochemical fecal occult-blood test for colorectal cancer between the stool specimens obtained during the routine screening and those during the digital rectal examination. METHODOLOGY: One hundred and fourteen patients with colorectal cancer and 228 healthy controls served as subjects of the study. Fecal occult-blood was tested by both of two methods; by the routine screening and by the digital rectal examination, and the sensitivity and specificity of an immunochemical fecal occult-blood test were determined in these two methods. RESULTS: The sensitivity and specificity were 79.8% and 96.5% in the routine screening method, and 86.0% and 79.8% in the digital rectal examination method, respectively, showing a significant difference in the specificity (P < 0.01) between these two stool collection methods. There was no significant difference in the sensitivity between these two stool collection methods. CONCLUSIONS: These findings indicate that the stool specimens collected at the time of the digital rectal examination is not suitable for testing of fecal occult-blood.
BACKGROUND/AIMS: To compare the diagnostic accuracy of an immunochemical fecal occult-blood test for colorectal cancer between the stool specimens obtained during the routine screening and those during the digital rectal examination. METHODOLOGY: One hundred and fourteen patients with colorectal cancer and 228 healthy controls served as subjects of the study. Fecal occult-blood was tested by both of two methods; by the routine screening and by the digital rectal examination, and the sensitivity and specificity of an immunochemical fecal occult-blood test were determined in these two methods. RESULTS: The sensitivity and specificity were 79.8% and 96.5% in the routine screening method, and 86.0% and 79.8% in the digital rectal examination method, respectively, showing a significant difference in the specificity (P < 0.01) between these two stool collection methods. There was no significant difference in the sensitivity between these two stool collection methods. CONCLUSIONS: These findings indicate that the stool specimens collected at the time of the digital rectal examination is not suitable for testing of fecal occult-blood.