OBJECTIVE: To compare cranial ultrasound studies and neurodevelopmental outcome of preterm infants affected by maternal floor infarction (MFI) of the placenta to gestational age-matched controls over an 8-year period from a single institution. STUDY DESIGN: Retrospective case/control study. RESULTS: Compared to gestational age-matched controls, infants born to mothers with MFI had a higher incidence of CNS injury on neonatal cranial ultrasound examinations and at follow-up were more likely to have a suspicious or abnormal neurologic examination. MFI cases had lower developmental scores in all areas tested and were more likely to have neurodevelopmental impairment. CONCLUSION: Infants born to mothers with MFI should have serial neonatal cranial ultrasound examinations to detect CNS injury and neurodevelopmental assessment during early childhood.
OBJECTIVE: To compare cranial ultrasound studies and neurodevelopmental outcome of preterm infants affected by maternal floor infarction (MFI) of the placenta to gestational age-matched controls over an 8-year period from a single institution. STUDY DESIGN: Retrospective case/control study. RESULTS: Compared to gestational age-matched controls, infants born to mothers with MFI had a higher incidence of CNS injury on neonatal cranial ultrasound examinations and at follow-up were more likely to have a suspicious or abnormal neurologic examination. MFI cases had lower developmental scores in all areas tested and were more likely to have neurodevelopmental impairment. CONCLUSION:Infants born to mothers with MFI should have serial neonatal cranial ultrasound examinations to detect CNS injury and neurodevelopmental assessment during early childhood.
Authors: Amy E Whitten; Roberto Romero; Steven J Korzeniewski; Adi L Tarca; Alyse G Schwartz; Lami Yeo; Zhong Dong; Sonia S Hassan; Tinnakorn Chaiworapongsa Journal: Am J Obstet Gynecol Date: 2013-01-17 Impact factor: 8.661
Authors: Jill K Tjon; Phillis Lakeman; Elisabeth van Leeuwen; Quinten Waisfisz; Marjan M Weiss; Gita M B Tan-Sindhunata; Peter G J Nikkels; Patrick J P van der Voorn; Gajja S Salomons; George L Burchell; Ingeborg H Linskens; Bloeme J van der Knoop; Johanna I P de Vries Journal: Mol Genet Genomic Med Date: 2021-10-12 Impact factor: 2.183