Literature DB >> 11946633

Inhibition of cholesterol synthesis by (-)-hydroxycitrate in perfused rat liver. Evidence for an extramitochondrial mevalonate synthesis from acetyl coenzyme A.

C Barth1, J Hackenschmidt, H Ullmann, K Decker.   

Abstract

Entities:  

Year:  1972        PMID: 11946633     DOI: 10.1016/0014-5793(72)80266-7

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


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  9 in total

1.  Regulation of cholesterol synthesis in rat adrenal gland through coordinate control of 3-hydroxy-3-methylglutaryl coenzyme A synthase and reductase activities.

Authors:  S Balasubramaniam; J L Goldstein; M S Brown
Journal:  Proc Natl Acad Sci U S A       Date:  1977-04       Impact factor: 11.205

Review 2.  Compartmentation of the early steps of cholesterol biosynthesis in mammalian liver.

Authors:  K Decker; C Barth
Journal:  Mol Cell Biochem       Date:  1973-12-15       Impact factor: 3.396

3.  Effect of (-)-hydroxycitrate upon the accumulation of lipid in the rat. I. Lipogenesis.

Authors:  A C Sullivan; J Triscari; J G Hamilton; O N Miller; V R Wheatley
Journal:  Lipids       Date:  1974-02       Impact factor: 1.880

4.  Comparative effects of (--)-hydroxycitrate and (+)-allo-hydroxycitrate on acetyl CoA carboxylase and fatty acid and cholesterol synthesis in vivo.

Authors:  J Triscari; A C Sullivan
Journal:  Lipids       Date:  1977-04       Impact factor: 1.880

5.  The metabolic route by which oleate is converted into cholesterol in rat hepatocytes.

Authors:  G F Gibbons; C P Attwell Thomas; C R Pullinger
Journal:  Biochem J       Date:  1986-04-01       Impact factor: 3.857

6.  Hupolipidemic activity of (--)-hydroxycitrate.

Authors:  J G Hamilton; A C Sullivan; D Kritchevsky
Journal:  Lipids       Date:  1977-01       Impact factor: 1.880

7.  The role of ATP citrate-lyase in the metabolic regulation of plasma lipids. Hypolipidaemic effects of SB-204990, a lactone prodrug of the potent ATP citrate-lyase inhibitor SB-201076.

Authors:  N J Pearce; J W Yates; T A Berkhout; B Jackson; D Tew; H Boyd; P Camilleri; P Sweeney; A D Gribble; A Shaw; P H Groot
Journal:  Biochem J       Date:  1998-08-15       Impact factor: 3.857

8.  AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism.

Authors:  Stephen L Pinkosky; Sergey Filippov; Rai Ajit K Srivastava; Jeffrey C Hanselman; Cheryl D Bradshaw; Timothy R Hurley; Clay T Cramer; Mark A Spahr; Ashley F Brant; Jacob L Houghton; Chris Baker; Mark Naples; Khosrow Adeli; Roger S Newton
Journal:  J Lipid Res       Date:  2012-11-01       Impact factor: 5.922

9.  Measurement of the absolute rates of cholesterol biosynthesis in isolated rat liver cells.

Authors:  G F Gibbons; C R Pullinger
Journal:  Biochem J       Date:  1977-02-15       Impact factor: 3.857

  9 in total

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