Literature DB >> 11944783

Renal cell carcinoma in patients with prior spinal cord injury.

S B Brandes1, J B Smith, W E Longo, K S Virgo, F E Johnson.   

Abstract

INTRODUCTION: In patients with spinal cord injury (SCI), abdominal diseases such as renal carcinoma are often diagnosed and treated late in their course.
METHODS: A population-based retrospective review of SCI patients receiving care for renal cell carcinoma (RCC) in all Department of Veterans Affairs (DVA) medical centers was conducted for fiscal years 1988 to 1998.
RESULTS: Of 96 patients identified, 57 were evaluable and 27 met study criteria. The mean patient age was 59 (range, 41-79 years). The mean time between SCI and treatment for RCC was 25 years (range, 1-51 years). All patients were men; 22/27 (81%) had 1 or more comorbid conditions. RCC was an incidental finding on surveillance imaging studies in 81% (22/27) of the patients. All 27 patients were treated surgically, 74% (20/27) by radical nephrectomy and 26% (7/27) by partial nephrectomy. All tumors were renal cell adenocarcinomas. Pathological staging by the tumor, nodes, and metastasis system was possible in 25; 92% (23/25) of tumors were stage I and 8% (2/25) were stage II. Postoperative morbidity occurred in 56% (15/27), and death occurred in 7% (2/27).
CONCLUSION: In SCI patients in the DVA system, diagnosis of RCC is usually the result of an incidental finding on surveillance imaging. Tumors are diagnosed at early stages and partial nephrectomy is often feasible. Many of the postoperative complications are related to the SCI, and may be preventable.

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Year:  2001        PMID: 11944783     DOI: 10.1080/10790268.2001.11753582

Source DB:  PubMed          Journal:  J Spinal Cord Med        ISSN: 1079-0268            Impact factor:   1.985


  2 in total

1.  Pulmonary resection for non-small cell lung cancer in patients with prior spinal cord injury.

Authors:  Louis S Brunworth; Dharson Dharmasena; Katherine S Virgo; Frank E Johnson
Journal:  J Spinal Cord Med       Date:  2006       Impact factor: 1.985

Review 2.  The management of neurogenic lower urinary tract dysfunction after spinal cord injury.

Authors:  Jean-Jacques Wyndaele
Journal:  Nat Rev Urol       Date:  2016-10-25       Impact factor: 14.432

  2 in total

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