| Literature DB >> 11943537 |
Lisa N Kinch1, Milton H Saier, Nick V Grishin.
Abstract
Sec61p/SecYEG complexes mediate protein translocation across membranes and are present in both eukaryotes and bacteria. Whereas homologues of Sec61alpha/SecY and Sec61gamma/SecE exist in archaea, identification of the third component (Sec61beta or SecG) has remained elusive. Using PSI-BLAST, the archaeal counterpart of Sec61beta has been detected. With the identification of the Sec61beta motif, functions for a universal family of archaeal proteins can be predicted and the archaeal translocon system can be definitively detected.Entities:
Mesh:
Substances:
Year: 2002 PMID: 11943537 DOI: 10.1016/s0968-0004(01)02055-2
Source DB: PubMed Journal: Trends Biochem Sci ISSN: 0968-0004 Impact factor: 13.807