BACKGROUND: Immediate breast reconstruction is often performed after mastectomy for breast cancer. There has been concern that this will result in a delay in initiating chemotherapy and, as a consequence, may adversely impact survival. In this study we sought to determine whether immediate breast reconstruction affects the interval between surgery and adjuvant chemotherapy. METHODS: A single institution retrospective analysis was made using the institutional tumor registry and chart reviews. RESULTS: Forty-nine patients were identified who had undergone mastectomy with immediate reconstruction followed by adjuvant chemotherapy. They were compared with 308 patients undergoing mastectomy without reconstruction. Patients who underwent reconstruction were overall younger (46 versus 55, P <0.001), and had more advanced disease. The time to chemotherapy was significantly longer in the group receiving no reconstruction: 53 versus 41 days (P = 0.039). The type of reconstruction did not affect the time to chemotherapy. CONCLUSIONS: Immediate reconstruction after mastectomy does not increase the time to chemotherapy compared with mastectomy alone.
BACKGROUND: Immediate breast reconstruction is often performed after mastectomy for breast cancer. There has been concern that this will result in a delay in initiating chemotherapy and, as a consequence, may adversely impact survival. In this study we sought to determine whether immediate breast reconstruction affects the interval between surgery and adjuvant chemotherapy. METHODS: A single institution retrospective analysis was made using the institutional tumor registry and chart reviews. RESULTS: Forty-nine patients were identified who had undergone mastectomy with immediate reconstruction followed by adjuvant chemotherapy. They were compared with 308 patients undergoing mastectomy without reconstruction. Patients who underwent reconstruction were overall younger (46 versus 55, P <0.001), and had more advanced disease. The time to chemotherapy was significantly longer in the group receiving no reconstruction: 53 versus 41 days (P = 0.039). The type of reconstruction did not affect the time to chemotherapy. CONCLUSIONS: Immediate reconstruction after mastectomy does not increase the time to chemotherapy compared with mastectomy alone.
Authors: Amy K Alderman; E Dale Collins; Anne Schott; Melissa E Hughes; Rebecca A Ottesen; Richard L Theriault; Yu-Ning Wong; Jane C Weeks; Joyce C Niland; Stephen B Edge Journal: Cancer Date: 2010-04-01 Impact factor: 6.860
Authors: Yue-Yung Hu; Christine M Weeks; Haejin In; Christopher M Dodgion; Mehra Golshan; Yoon S Chun; Michael J Hassett; Katherine A Corso; Xiangmei Gu; Stuart R Lipsitz; Caprice C Greenberg Journal: Cancer Date: 2011-01-24 Impact factor: 6.860
Authors: Ida Oberhauser; Jasmin Zeindler; Mathilde Ritter; Jeremy Levy; Giacomo Montagna; Robert Mechera; Savas Deniz Soysal; Liliana Castrezana López; Veronica D'Amico; Elisabeth Artemis Kappos; Fabienne Dominique Schwab; Madleina Müller; Christian Kurzeder; Martin Haug; Walter Paul Weber Journal: Breast Care (Basel) Date: 2020-11-25 Impact factor: 2.860
Authors: Stefano Zurrida; Fabio Bassi; Paolo Arnone; Stefano Martella; Andres Del Castillo; Rafael Ribeiro Martini; M Eugenia Semenkiw; Pietro Caldarella Journal: Int J Surg Oncol Date: 2011-06-05