Literature DB >> 11943003

Neuropsychological functioning in older people with type 2 diabetes: the effect of controlling for confounding factors.

K G Asimakopoulou1, S E Hampson, N J Morrish.   

Abstract

AIMS AND METHODS: Neuropsychological functioning was examined in a group of 33 older (mean age 62.40 +/- 9.62 years) people with Type 2 diabetes (Group 1) and 33 non-diabetic participants matched with Group 1 on age, sex, premorbid intelligence and presence of hypertension and cardio/cerebrovascular conditions (Group 2).
RESULTS: Data statistically corrected for confounding factors obtained from the diabetic group were compared with the matched control group. The results suggested small cognitive deficits in diabetic people's verbal memory and mental flexibility (Logical Memory A and SS7). No differences were seen between the two samples in simple and complex visuomotor attention, sustained complex visual attention, attention efficiency, mental double tracking, implicit memory, and self-reported memory problems.
CONCLUSIONS: These findings indicate minimal cognitive impairment in relatively uncomplicated Type 2 diabetes and demonstrate the importance of control and matching for confounding factors.

Entities:  

Mesh:

Year:  2002        PMID: 11943003     DOI: 10.1046/j.1464-5491.2002.00680.x

Source DB:  PubMed          Journal:  Diabet Med        ISSN: 0742-3071            Impact factor:   4.359


  7 in total

1.  Impairment of executive cognitive control in type 2 diabetes, and its effects on health-related behavior and use of health services.

Authors:  Dinh Tran; Judith Baxter; Richard F Hamman; Jim Grigsby
Journal:  J Behav Med       Date:  2013-02-22

2.  The evaluation of the Turkish version of the Well-being Questionnaire (WBQ-22) in patients with Type 2 diabetes: the effects of diabetic complications.

Authors:  H Savli; A Sevinc
Journal:  J Endocrinol Invest       Date:  2005-09       Impact factor: 4.256

Review 3.  Assessing premorbid cognitive ability in adults with type 2 diabetes mellitus--a review with implications for future intervention studies.

Authors:  Rachel Heloise Xiwen Wong; Andrew Scholey; Peter Ranald Charles Howe
Journal:  Curr Diab Rep       Date:  2014       Impact factor: 4.810

4.  Uncontrolled diabetes increases the risk of Alzheimer's disease: a population-based cohort study.

Authors:  W L Xu; E von Strauss; C X Qiu; B Winblad; L Fratiglioni
Journal:  Diabetologia       Date:  2009-03-12       Impact factor: 10.122

5.  Word-stem priming and recognition in type 2 diabetes mellitus, Alzheimer's disease patients and healthy older adults.

Authors:  María Teresa Redondo; José Luís Beltrán-Brotóns; José Manuel Reales; Soledad Ballesteros
Journal:  Exp Brain Res       Date:  2015-08-08       Impact factor: 1.972

Review 6.  A look inside the diabetic brain: Contributors to diabetes-induced brain aging.

Authors:  Shayna A Wrighten; Gerardo G Piroli; Claudia A Grillo; Lawrence P Reagan
Journal:  Biochim Biophys Acta       Date:  2008-11-05

7.  Metabolic and vascular determinants of impaired cognitive performance and abnormalities on brain magnetic resonance imaging in patients with type 2 diabetes.

Authors:  S M Manschot; G J Biessels; H de Valk; A Algra; G E H M Rutten; J van der Grond; L J Kappelle
Journal:  Diabetologia       Date:  2007-09-02       Impact factor: 10.122

  7 in total

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