Literature DB >> 11940928

Isoflurane Anesthesia Therapy: A Replacement for ECT in Depressive Disorders?

Lawrence B. Greenberg1, John Gage, Stephen Vitkun, Max Fink.   

Abstract

Isoflurane anesthesia therapy (IAT) has been suggested to have persistent antidepressant activity. In a replication trial, IAT was performed in six patients who had a recurrence of a severe depressive episode, previously treated with ECT. In 21 of 26 IAT sessions, an isoelectric electroencephalogram lasting between 5 and 12 min was recorded. Clinical antidepressant activity was not observed. It is concluded that IAT is not an effective replacement for ECT in the treatment of major depressive disorders.

Entities:  

Year:  1987        PMID: 11940928

Source DB:  PubMed          Journal:  Convuls Ther        ISSN: 0749-8055


  7 in total

1.  Isoflurane produces antidepressant effects inducing BDNF-TrkB signaling in CUMS mice.

Authors:  Sha-Sha Zhang; Yu-Hua Tian; Song-Jun Jin; Wen-Cheng Wang; Jing-Xin Zhao; Xiao-Ming Si; Li Zhang; Hong Xu; Jing-Yu Jin
Journal:  Psychopharmacology (Berl)       Date:  2019-06-13       Impact factor: 4.530

2.  Isoflurane produces antidepressant effects and induces TrkB signaling in rodents.

Authors:  Hanna Antila; Maria Ryazantseva; Dina Popova; Pia Sipilä; Ramon Guirado; Samuel Kohtala; Ipek Yalcin; Jesse Lindholm; Liisa Vesa; Vinicius Sato; Joshua Cordeira; Henri Autio; Mikhail Kislin; Maribel Rios; Sâmia Joca; Plinio Casarotto; Leonard Khiroug; Sari Lauri; Tomi Taira; Eero Castrén; Tomi Rantamäki
Journal:  Sci Rep       Date:  2017-08-10       Impact factor: 4.379

3.  Propofol for Treatment-Resistant Depression: A Pilot Study.

Authors:  Brian J Mickey; Andrea T White; Anna M Arp; Kolby Leonardi; Marina M Torres; Adam L Larson; David H Odell; Sara A Whittingham; Michael M Beck; Jacob E Jessop; Derek J Sakata; Lowry A Bushnell; Matthew D Pierson; Daniela Solzbacher; E Jeremy Kendrick; Howard R Weeks; Alan R Light; Kathleen C Light; Scott C Tadler
Journal:  Int J Neuropsychopharmacol       Date:  2018-12-01       Impact factor: 5.176

Review 4.  Relevance of Cortical and Hippocampal Interneuron Functional Diversity to General Anesthetic Mechanisms: A Narrative Review.

Authors:  Iris A Speigel; Hugh C Hemmings
Journal:  Front Synaptic Neurosci       Date:  2022-01-26

5.  Antidepressant and neurocognitive effects of isoflurane anesthesia versus electroconvulsive therapy in refractory depression.

Authors:  Howard R Weeks; Scott C Tadler; Kelly W Smith; Eli Iacob; Mikala Saccoman; Andrea T White; Joshua D Landvatter; Gordon J Chelune; Yana Suchy; Elaine Clark; Michael K Cahalan; Lowry Bushnell; Derek Sakata; Alan R Light; Kathleen C Light
Journal:  PLoS One       Date:  2013-07-26       Impact factor: 3.240

6.  Leukocyte Gene Expression in Patients with Medication Refractory Depression before and after Treatment with ECT or Isoflurane Anesthesia: A Pilot Study.

Authors:  E Iacob; S C Tadler; K C Light; H R Weeks; K W Smith; A T White; R W Hughen; T A VanHaitsma; L A Bushnell; A R Light
Journal:  Depress Res Treat       Date:  2014-04-13

7.  Isoflurane but Not Halothane Prevents and Reverses Helpless Behavior: A Role for EEG Burst Suppression?

Authors:  P Leon Brown; Panos Zanos; Leiming Wang; Greg I Elmer; Todd D Gould; Paul D Shepard
Journal:  Int J Neuropsychopharmacol       Date:  2018-08-01       Impact factor: 5.176

  7 in total

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