Wei Liu1, Ti Tong, Zhendong Ji, Zhenhe Zhang. 1. Department of Thoracic Surgery, The First Teaching Hospital of Norman Bethune University of Medical Sciences, Changchun 130021, China. davidliuw@hotmail.com
Abstract
OBJECTIVE: To study the factors affecting the long-term prognosis of patients with myasthenia gravis (MG) after thymectomy. METHODS: 170 MG patients who had undergone thymectomies were studied retrospectively. Among them, 124 patients received long-term follow-up for more than 40 months postoperatively. The COX regression analysis model was used to analyze the factors that may influence the long-term prognosis. These factors included thymus pathology, patient gender, age, duration of disease at the time of surgery, preoperative Osserman classification and medication. RESULTS: The research showed that thymus pathology was the single independent factor that affected the postoperative long-term prognosis. The long-term survival rates differed significantly with thymus pathological types: hyperplasia > benign thymoma > atrophy > malignant thymoma (P < 0.05). CONCLUSION: The different pathological types of the thymus were the important factor affecting long-term survival in MG patients after thymectomy.
OBJECTIVE: To study the factors affecting the long-term prognosis of patients with myasthenia gravis (MG) after thymectomy. METHODS: 170 MGpatients who had undergone thymectomies were studied retrospectively. Among them, 124 patients received long-term follow-up for more than 40 months postoperatively. The COX regression analysis model was used to analyze the factors that may influence the long-term prognosis. These factors included thymus pathology, patient gender, age, duration of disease at the time of surgery, preoperative Osserman classification and medication. RESULTS: The research showed that thymus pathology was the single independent factor that affected the postoperative long-term prognosis. The long-term survival rates differed significantly with thymus pathological types: hyperplasia > benign thymoma > atrophy > malignant thymoma (P < 0.05). CONCLUSION: The different pathological types of the thymus were the important factor affecting long-term survival in MGpatients after thymectomy.
Authors: Ranhel C De Roxas; Marjorie Anne C Bagnas; Jobelle Joyce Anne R Baldonado; Jonathan P Rivera; Artemio A Roxas Journal: Front Neurol Date: 2016-06-21 Impact factor: 4.003