Literature DB >> 11939424

Shaping individuality: human inheritable germ line gene modification.

M Salvi.   

Abstract

In this paper I deal with ethical factors surrounding germline gene therapy. Such implications include intergenerational responsibility, human dignity, moral status of embryos and so on. I will explore the relevance of the above mentioned issues to discuss the ethical implication of human germline gene therapy (HGLT). We will see that most of arguments claimed by bioethicists do not provide valid reason to oppose HGLT. I will propose an alternative view, based on personal identity issues, to discuss the ethics of human inheritable gene modification.

Entities:  

Keywords:  Analytical Approach; Biomedical and Behavioral Research; Genetics and Reproduction

Mesh:

Year:  2001        PMID: 11939424     DOI: 10.1023/a:1014496531938

Source DB:  PubMed          Journal:  Theor Med Bioeth        ISSN: 1386-7415


  11 in total

1.  Gene therapy death prompts review of adenovirus vector.

Authors:  E Marshall
Journal:  Science       Date:  1999-12-17       Impact factor: 47.728

2.  Genetic enhancement in humans.

Authors:  J W Gordon
Journal:  Science       Date:  1999-03-26       Impact factor: 47.728

3.  Commentary on "Genetic harm: bitten by the body that keeps you?

Authors:  Noam J Zohar
Journal:  Bioethics       Date:  1991-10       Impact factor: 1.898

4.  ELSI: Cambridge Symposium -- LeRoy Walters on "Ethical issues in human gene therapy.

Authors: 
Journal:  Hum Genome News       Date:  1999-02

5.  RAC confronts in utero gene therapy proposals.

Authors:  J Couzin
Journal:  Science       Date:  1998-10-02       Impact factor: 47.728

6.  NIH launches discussion of in utero gene therapy...and seeks to repair 'flaw' in review process.

Authors:  M Wadman
Journal:  Nature       Date:  1998-10-01       Impact factor: 49.962

7.  IVF: regulation or prohibition?

Authors:  A McLaren
Journal:  Nature       Date:  1989-11-30       Impact factor: 49.962

Review 8.  Prospects for in utero human gene therapy.

Authors:  E D Zanjani; W F Anderson
Journal:  Science       Date:  1999-09-24       Impact factor: 47.728

9.  "Playing God" and germline intervention.

Authors:  T Peters
Journal:  J Med Philos       Date:  1995-08

10.  Prospects for human gene therapy.

Authors:  W F Anderson
Journal:  Science       Date:  1984-10-26       Impact factor: 47.728

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