| Literature DB >> 11937713 |
Noriyuki Kioka1, Kazumitsu Ueda, Teruo Amachi.
Abstract
Adaptor proteins, composed of two or more protein-protein interacting modules without enzymatic activity, regulate various cellular functions. Vinexin, CAP/ponsin, and ArgBP2 constitute a novel adaptor protein family. They have a novel conserved region homologous to the active peptide sorbin, as well as three SH3 (src homology 3) domains. A number of proteins binding to this adaptor family have been identified. There is accumulating evidence that this protein family regulates cell adhesion, cytoskeletal organization, and growth factor signaling. This review will summarize the structure and the function of proteins in this family.Entities:
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Year: 2002 PMID： 11937713 DOI： 10.1247/csf.27.1
Source DB: PubMed Journal: Cell Struct Funct ISSN： 0386-7196 Impact factor: 2.212