Literature DB >> 11937353

Efficient synthesis of 'redox-switched' naphthoquinone thiol-crown ethers and their biological activity evaluation.

Sheng Tung Huang1, Hsien Shou Kuo, Chiao Long Hsiao, Yuh Ling Lin.   

Abstract

Series of naphthoquinone thiol-crown ethers had been prepared. The antibacterial, antifungal, and cytotoxic activities of these synthetic naphthoquinone thiol-crown ethers were investigated. All of the compounds tested displayed antibacterial, cytotoxic and antifungal activities. The bis-naphthoquinone thiol-crown ether 7a was the most potent inhibitor among tested analogues against Staphylococcus aureus methicillin resistance with MIC value of 2.68 microM.

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Year:  2002        PMID： 11937353     DOI： 10.1016/s0968-0896(02)00004-4

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  8 in total

1.  Anticancer activity and SAR studies of substituted 1,4-naphthoquinones.

Authors:  Deepak Bhasin; Somsundaram N Chettiar; Jonathan P Etter; May Mok; Pui-Kai Li
Journal:  Bioorg Med Chem       Date:  2013-05-18       Impact factor: 3.641

2.  Acylated and alkylated benzo(crown-ethers) form ion-dependent ion channels in biological membranes.

Authors:  Willy Carrasquel-Ursulaez; Mahzad Dehghany; Corey L Jones; Vinaykumar Idikuda; Brian Lu; Jennifer M Schomaker; Baron Chanda
Journal:  Biophys J       Date:  2022-02-02       Impact factor: 4.033

3.  The p53-dependent apoptotic pathway of breast cancer cells (BC-M1) induced by the bis-type bioreductive compound aziridinylnaphthoquinone.

Authors:  Yu-Ping Yang; Hsien-Shou Kuo; Hsin-Da Tsai; Yi-Chen Peng; Yuh-Ling Lin
Journal:  Breast Cancer Res       Date:  2004-11-04       Impact factor: 6.466

4.  Synthesis of Selenium-Quinone Hybrid Compounds with Potential Antitumor Activity via Rh-Catalyzed C-H Bond Activation and Click Reactions.

Authors:  Guilherme A M Jardim; Daisy J B Lima; Wagner O Valença; Daisy J B Lima; Bruno C Cavalcanti; Claudia Pessoa; Jamal Rafique; Antonio L Braga; Claus Jacob; Eufrânio N da Silva Júnior; Eduardo H G da Cruz
Journal:  Molecules       Date:  2017-12-30       Impact factor: 4.411

5.  1H and 13C NMR chemical shifts of 2-n-alkylamino-naphthalene-1,4-diones.

Authors:  Rishikesh Patil; Mahesh Jadhav; Sunita Salunke-Gawali; Dipali N Lande; Shridhar P Gejji; Debamitra Chakravarty
Journal:  Heliyon       Date:  2021-01-28

6.  Modification of phospholipid bilayers induced by sulfurated naphthoquinones.

Authors:  Claudio Di Vitta; Liliana Marzorati; Sérgio S Funari
Journal:  J Lipids       Date:  2013-03-30

7.  Ionically Crosslinked Chitosan Membranes Used as Drug Carriers for Cancer Therapy Application.

Authors:  Alecsandra Ferreira Tomaz; Sandra Maria Sobral de Carvalho; Rossemberg Cardoso Barbosa; Suédina M L Silva; Marcos Antônio Sabino Gutierrez; Antônio Gilson B de Lima; Marcus Vinícius L Fook
Journal:  Materials (Basel)       Date:  2018-10-20       Impact factor: 3.623

Review 8.  The diverse mechanisms and anticancer potential of naphthoquinones.

Authors:  Carolina Escardó Pereyra; Rafael Ferreira Dantas; Sabrina Baptista Ferreira; Luciano Pinho Gomes; Floriano Paes Silva-Jr
Journal:  Cancer Cell Int       Date:  2019-08-02       Impact factor: 5.722
  8 in total

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