Literature DB >> 1193731

Effect of the antitumor antibiotic chromomycin A3 on the humoral immune response in rats.

R Nayak, K S Prasad, M Sirsi.   

Abstract

Chromomycin A3 (250 mug/kg) suppressed the humoral immune response in rats against sheep erythrocytes when administered 48 h or later after antigenic stimulus. The antibiotic at this dose enhanced immunity when given along with or before antigen administration. The natural heterohemagglutinin levels in rabbits and guinea pigs were not affected by the antibiotic (10 mug/kg per day x 7).

Entities:  

Mesh：

Substances：

Year:  1975        PMID： 1193731      PMCID： PMC415379          DOI： 10.1128/iai.12.5.943-946.1975

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  13 in total

1.  Studies on the effect of some antitumour antibiotics on mouse fibrosarcoma.

Authors:  R Nayak; K S Prasad; M Sirsi
Journal:  Indian J Med Res       Date:  1975-07       Impact factor: 2.375

Review 2.  Immunological aspects of Burkitt's lymphoma.

Authors:  G Klein
Journal:  Adv Immunol       Date:  1971       Impact factor: 3.543

3.  [Inhibition of multiplication of RNA-phages by chromomycin A3].

Authors:  H Kobayashi
Journal:  Seikagaku       Date:  1966-11

4.  Specificity of natural heterohaemagglutinins of some laboratory animals.

Authors:  R Nayak; M Sirsi
Journal:  Indian J Exp Biol       Date:  1972-09       Impact factor: 0.818

Review 5.  Immunosuppressive drugs.

Authors:  T Makinodan; G W Santos; R P Quinn
Journal:  Pharmacol Rev       Date:  1970-06       Impact factor: 25.468

Review 6.  Chemical suppression of adaptive immunity.

Authors:  A E Gabrielsen; R A Good
Journal:  Adv Immunol       Date:  1967       Impact factor: 3.543

7.  Heat stability and 2-mercaptoethanol sensitivity of natural heterohaemagglutinins of some laboratory animals.

Authors:  R Nayak; M Sirsi
Journal:  Indian J Exp Biol       Date:  1972-07       Impact factor: 0.818

Review 8.  Olivomycin, mithramycin, chromomycin: three related cancerostatic antibiotics.

Authors:  G F Gause
Journal:  Adv Chemother       Date:  1965

9.  Variation of the supercoils in closed circular DNA by binding of antibiotics and drugs: evidence for molecular models involving intercalation.

Authors:  M Waring
Journal:  J Mol Biol       Date:  1970-12-14       Impact factor: 5.469

Review 10.  Relations between immunity and malignancy.

Authors:  R A Good
Journal:  Proc Natl Acad Sci U S A       Date:  1972-04       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.