OBJECTIVE: To monitor gonadotropin and ovarian hormone levels in relation to sleep duration in normally cycling women. DESIGN: Observational and cross-sectional study. SETTING: Multicentric collaborative study. PATIENT(S): One hundred six healthy and normally cycling women, aged 19 to 44 years, with cycle lengths of 24 to 34 days. INTERVENTION(S): Follow-up during one to four consecutive cycles with daily urine collection. MAIN OUTCOME MEASURE(S): Urine concentrations of LH, FSH, estrone-3-glucuronide (E1-3-G), and pregnanediol-3-alpha-glucuronide (Pd-3alpha-G). Ultrasound determination of day of ovulation and estimation of sleep duration. RESULT(S): We found a significant association between FSH levels and sleep duration (P=.008). Follicle-stimulating hormone levels were 20% higher in long-time sleepers than in short-time sleepers. This association persisted whatever the age or the body mass index. There was no significant association between belonging to any group and LH, E1-3-G, or Pd-3alpha-G levels. CONCLUSION(S): Our results suggest that sleep duration could be related to FSH levels, although the study design did not allow us to establish a causal relationship nor to explain the physiological basis of the observed relationship.
OBJECTIVE: To monitor gonadotropin and ovarian hormone levels in relation to sleep duration in normally cycling women. DESIGN: Observational and cross-sectional study. SETTING: Multicentric collaborative study. PATIENT(S): One hundred six healthy and normally cycling women, aged 19 to 44 years, with cycle lengths of 24 to 34 days. INTERVENTION(S): Follow-up during one to four consecutive cycles with daily urine collection. MAIN OUTCOME MEASURE(S): Urine concentrations of LH, FSH, estrone-3-glucuronide (E1-3-G), and pregnanediol-3-alpha-glucuronide (Pd-3alpha-G). Ultrasound determination of day of ovulation and estimation of sleep duration. RESULT(S): We found a significant association between FSH levels and sleep duration (P=.008). Follicle-stimulating hormone levels were 20% higher in long-time sleepers than in short-time sleepers. This association persisted whatever the age or the body mass index. There was no significant association between belonging to any group and LH, E1-3-G, or Pd-3alpha-G levels. CONCLUSION(S): Our results suggest that sleep duration could be related to FSH levels, although the study design did not allow us to establish a causal relationship nor to explain the physiological basis of the observed relationship.
Authors: Sarah Forbes-Robertson; Edward Dudley; Pankaj Vadgama; Christian Cook; Scott Drawer; Liam Kilduff Journal: Sports Med Date: 2012-03-01 Impact factor: 11.136
Authors: Jacqueline D Kloss; Michael L Perlis; Jessica A Zamzow; Elizabeth J Culnan; Clarisa R Gracia Journal: Sleep Med Rev Date: 2014-10-18 Impact factor: 11.609
Authors: Huiyong Zheng; Siobán D Harlow; Howard M Kravitz; Joyce Bromberger; Daniel J Buysse; Karen A Matthews; Ellen B Gold; Jane F Owens; Martica Hall Journal: Menopause Date: 2015-01 Impact factor: 2.953
Authors: Kara A Michels; Pauline Mendola; Karen C Schliep; Edwina H Yeung; Aijun Ye; Galit L Dunietz; Jean Wactawski-Wende; Keewan Kim; Joshua R Freeman; Enrique F Schisterman; Sunni L Mumford Journal: Chronobiol Int Date: 2019-11-28 Impact factor: 2.877
Authors: Jessicah S Collins; Jennifer P Beller; Christine Burt Solorzano; James T Patrie; R Jeffrey Chang; John C Marshall; Christopher R McCartney Journal: J Clin Endocrinol Metab Date: 2014-04-29 Impact factor: 5.958
Authors: Mary Fran Sowers; Huiyong Zheng; Howard M Kravitz; Karen Matthews; Joyce T Bromberger; Ellen B Gold; Jane Owens; Flavia Consens; Martica Hall Journal: Sleep Date: 2008-10 Impact factor: 5.849