Literature DB >> 11937045

Cell signaling: life or death decisions of ras proteins.

Larry A Feig1, Rachel J Buchsbaum.   

Abstract

The discovery of a new downstream target for the Ras GTPases - a Nore1-Mst1 protein complex - reveals a mechanism by which Ras can promote apoptosis, and suggests that the influence of Ras on cell survival or death depends upon the relative level of activation of its various target proteins.

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Year:  2002        PMID： 11937045     DOI： 10.1016/s0960-9822(02)00787-x

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  28 in total

1.  RASSF1A promoter methylation and Kras2 mutations in non small cell lung cancer.

Authors:  Jie Li; Zhongqiu Zhang; Zunyan Dai; Anthony P Popkie; Christoph Plass; Carl Morrison; Yian Wang; Ming You
Journal:  Neoplasia       Date:  2003 Jul-Aug       Impact factor: 5.715

2.  The Ras G Domain Lacks the Intrinsic Propensity to Form Dimers.

Authors:  Elizaveta A Kovrigina; Azamat R Galiakhmetov; Evgenii L Kovrigin
Journal:  Biophys J       Date:  2015-09-01       Impact factor: 4.033

3.  Oncogenic Ras and B-Raf proteins positively regulate death receptor 5 expression through co-activation of ERK and JNK signaling.

Authors:  You-Take Oh; Ping Yue; Wei Zhou; Justin M Balko; Esther P Black; Taofeek K Owonikoko; Fadlo R Khuri; Shi-Yong Sun
Journal:  J Biol Chem       Date:  2011-11-07       Impact factor: 5.157

4.  Activity of the Ste20-like kinase, SLK, is enhanced by homodimerization.

Authors:  Sierra Delarosa; Julie Guillemette; Joan Papillon; Ying-Shan Han; Arnold S Kristof; Andrey V Cybulsky
Journal:  Am J Physiol Renal Physiol       Date:  2011-06-15

5.  p75-Ras-GRF1 is a c-Jun/AP-1 target protein: its up regulation results in increased Ras activity and is necessary for c-Jun-induced nonadherent growth of Rat1a cells.

Authors:  Virna D Leaner; Howard Donninger; Chad A Ellis; Geoffrey J Clark; Michael J Birrer
Journal:  Mol Cell Biol       Date:  2005-04       Impact factor: 4.272

6.  Activation of sterile20-like kinase 1 in proteasome inhibitor bortezomib-induced apoptosis in oncogenic K-ras-transformed cells.

Authors:  Fuminori Teraishi; Wei Guo; Lidong Zhang; Fengqing Dong; John J Davis; Takehiko Sasazuki; Senji Shirasawa; Jinsong Liu; Bingliang Fang
Journal:  Cancer Res       Date:  2006-06-15       Impact factor: 12.701

7.  Myricetin induces apoptosis by inhibiting P21 activated kinase 1 (PAK1) signaling cascade in hepatocellular carcinoma.

Authors:  Soumya C Iyer; Ashidha Gopal; Devaraj Halagowder
Journal:  Mol Cell Biochem       Date:  2015-06-24       Impact factor: 3.396

8.  The differential effects of wild-type and mutated K-Ras on MST2 signaling are determined by K-Ras activation kinetics.

Authors:  David Romano; Helene Maccario; Carolanne Doherty; Niall P Quinn; Walter Kolch; David Matallanas
Journal:  Mol Cell Biol       Date:  2013-03-04       Impact factor: 4.272

9.  Structural comparison of human mammalian ste20-like kinases.

Authors:  Christopher J Record; Apirat Chaikuad; Peter Rellos; Sanjan Das; Ashley C W Pike; Oleg Fedorov; Brian D Marsden; Stefan Knapp; Wen Hwa Lee
Journal:  PLoS One       Date:  2010-08-06       Impact factor: 3.240

10.  Kinetic isotope effects in Ras-catalyzed GTP hydrolysis: evidence for a loose transition state.

Authors:  Xinlin Du; Gavin E Black; Paolo Lecchi; Fred P Abramson; Stephen R Sprang
Journal:  Proc Natl Acad Sci U S A       Date:  2004-06-03       Impact factor: 11.205
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