Literature DB >> 11936175

Determination of the dose characteristics in the near area of a new type of 192Ir-HDR afterloading source with a pinpoint ionization chamber.

C Gromoll1, A Karg.   

Abstract

Since the company MDS Nordion Haan GmbH introduced the new afterloading radiation unit GammaMed plus in 1998, new HDR Ir-192 sources with a diameter of 0.9 mm (formerly 1.1 mm) and a length of 4.5 mm (formerly 5.5 mm) have been used. With this equipment it is possible to treat peripheral vessels for prophylaxis of restenosis after percutaneous transluminal angioplasty (PTA). In this case a good knowledge of the dose characteristics in the near area is the prerequisite for safe application. In this study, the dose characteristics for this source type is investigated at close range by means of an ionization chamber. For the description of the dose characteristics, the radial dose distribution and the anisotropy function are used. The measurements were carried out using an ionization chamber, the so-called PinPoint chamber (Type PTW 31006, PTW Freiburg, Germany). The radial dose distribution was examined in the area of 0.26 to 12 cm. The anisotropy function was examined in the range from 0.5 to 5 cm (distance from the effective site of measurement to the source axis). The radial dose function was compared with the correction function k(as,w) (r), published in the German standard DIN 6809 part 2 (1991 Beuth Verlag, Berlin, Germany). In the area up to 4 cm (distance source-axis to measuring point) the deviation maximized up to 2%. The deviation climbs with greater distance from the source with results around 3%. The anisotropy function was compared with that used in the treatment planning system Abacus 3.0 of the same manufacturer. In the close range between 0.5 and 1 cm, there were some major variations (up to 10%) from the anisotropy function used in the planning system. The fault reduces itself with greater distance to under 2%. In view of the results presented in this paper further measurements of the anisotropy function in the close range from 0 to 1.5 cm from the source axis should be made. It can be seen that the function used in the planning system supplies results that are too high in comparison with the results of other authors. This concerns primarily the area of very small and very big angles.

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Year:  2002        PMID: 11936175

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  3 in total

Review 1.  Air kerma and absorbed dose standards for reference dosimetry in brachytherapy.

Authors:  T Sander
Journal:  Br J Radiol       Date:  2014-07-07       Impact factor: 3.039

2.  Value of diffusion weighted MR imaging as an early surrogate parameter for evaluation of tumor response to high-dose-rate brachytherapy of colorectal liver metastases.

Authors:  Christian Wybranski; Martin Zeile; David Löwenthal; Frank Fischbach; Maciej Pech; Friedrich-Wilhelm Röhl; Günther Gademann; Jens Ricke; Oliver Dudeck
Journal:  Radiat Oncol       Date:  2011-04-27       Impact factor: 3.481

3.  Dosimetric impact of an air passage on intraluminal brachytherapy for bronchus cancer.

Authors:  Hiroyuki Okamoto; Akihisa Wakita; Satoshi Nakamura; Shie Nishioka; Ako Aikawa; Toru Kato; Yoshihisa Abe; Kazuma Kobayashi; Koji Inaba; Naoya Murakami; Jun Itami
Journal:  J Radiat Res       Date:  2016-09-07       Impact factor: 2.724

  3 in total

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