Literature DB >> 11934935

Embryonic stem cell production through therapeutic cloning has fewer ethical problems than stem cell harvest from surplus IVF embryos.

J-E S Hansen1.   

Abstract

Restrictions on research on therapeutic cloning are questionable as they inhibit the development of a technique which holds promise for successful application of pluripotent stem cells in clinical treatment of severe diseases. It is argued in this article that the ethical concerns are less problematic using therapeutic cloning compared with using fertilised eggs as the source for stem cells. The moral status of an enucleated egg cell transplanted with a somatic cell nucleus is found to be more clearly not equivalent to that of a human being. Based on ethical considerations alone, research into therapeutic cloning should be encouraged in order to develop therapeutic applications of stem cells.

Entities:  

Keywords:  Analytical Approach; Biomedical and Behavioral Research; Genetics and Reproduction

Mesh:

Year:  2002        PMID: 11934935      PMCID: PMC1733544          DOI: 10.1136/jme.28.2.86

Source DB:  PubMed          Journal:  J Med Ethics        ISSN: 0306-6800            Impact factor:   2.903


  7 in total

1.  Europe confronts the embryonic stem cell research challenge.

Authors:  N Lenoir
Journal:  Science       Date:  2000-02-25       Impact factor: 47.728

Review 2.  Benefits and problems with cloning animals.

Authors:  L C Smith; V Bordignon; M Babkine; G Fecteau; C Keefer
Journal:  Can Vet J       Date:  2000-12       Impact factor: 1.008

3.  Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells.

Authors:  M Schuldiner; O Yanuka; J Itskovitz-Eldor; D A Melton; N Benvenisty
Journal:  Proc Natl Acad Sci U S A       Date:  2000-10-10       Impact factor: 11.205

4.  Embryonic stem cells differentiate into oligodendrocytes and myelinate in culture and after spinal cord transplantation.

Authors:  S Liu; Y Qu; T J Stewart; M J Howard; S Chakrabortty; T F Holekamp; J W McDonald
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-23       Impact factor: 11.205

5.  Potential and the early human.

Authors:  H Watt
Journal:  J Med Ethics       Date:  1996-08       Impact factor: 2.903

6.  Isolation of pluripotent embryonic stem cells from reprogrammed adult mouse somatic cell nuclei.

Authors:  M J Munsie; A E Michalska; C M O'Brien; A O Trounson; M F Pera; P S Mountford
Journal:  Curr Biol       Date:  2000-08-24       Impact factor: 10.834

7.  Clinical and pathologic features of cloned transgenic calves and fetuses (13 case studies).

Authors:  J R Hill; A J Roussel; J B Cibelli; J F Edwards; N L Hooper; M W Miller; J A Thompson; C R Looney; M E Westhusin; J M Robl; S L Stice
Journal:  Theriogenology       Date:  1999-06       Impact factor: 2.740

  7 in total
  4 in total

1.  The ethical dilemma of embryonic stem cell research.

Authors:  Nabeel Manzar; Bushra Manzar; Nuzhat Hussain; M Fawwad Ahmed Hussain; Sajjad Raza
Journal:  Sci Eng Ethics       Date:  2011-10-29       Impact factor: 3.525

2.  The gap between law and ethics in human embryonic stem cell research: overcoming the effect of U.S. federal policy on research advances and public benefit.

Authors:  Patrick L Taylor
Journal:  Sci Eng Ethics       Date:  2005-10       Impact factor: 3.525

3.  Human therapeutic cloning (NTSC): applying research from mammalian reproductive cloning.

Authors:  Andrew J French; Samuel H Wood; Alan O Trounson
Journal:  Stem Cell Rev       Date:  2006       Impact factor: 5.739

4.  Effect of two prostaglandin injections on days 5 and 6 in a timed AI protocol after estrus expression on pregnancy outcomes in dairy cows during cold or hot seasons of the year.

Authors:  Mufeed A Alnimer; Mohamed A Abedal-Majed; Ahmad I Shamoun
Journal:  Arch Anim Breed       Date:  2019-04-10
  4 in total

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