| Literature DB >> 11931990 |
Armando A Genazzani1, Richard A Billington.
Abstract
Recently, nicotinic acid adenine dinucleotide phosphate (NAADP) has been shown, using different techniques, to mobilize intracellular Ca2+ stores in invertebrate, lower vertebrate, plant and mammalian cells. This endogenous molecule might play an atypical role in Ca2+ signalling by coordinating the responses of other Ca2+-releasing messengers. Furthermore, radioligand binding experiments have provided an insight into how desensitization of the NAADP receptor might occur.Entities:
Mesh:
Substances:
Year: 2002 PMID: 11931990 DOI: 10.1016/s0165-6147(00)01990-8
Source DB: PubMed Journal: Trends Pharmacol Sci ISSN: 0165-6147 Impact factor: 14.819