Literature DB >> 11931713

Searching for the mountains of the moon: genome scans for atherosclerosis.

Michael A Province1.   

Abstract

Several research groups have begun mounting large, ambitious family studies to map genes for atherosclerosis, heart disease, and their major risk factors using whole genome linkage and/or disequilibrium scans. Some of the problems, pitfalls, and challenges of this exciting effort are examined and illustrated with lessons from an earlier mapping problem.

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Year:  2002        PMID: 11931713     DOI: 10.1007/s11883-002-0016-4

Source DB:  PubMed          Journal:  Curr Atheroscler Rep        ISSN: 1523-3804            Impact factor:   5.113


  37 in total

1.  Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. I. Likelihood formulation and simulation results.

Authors:  J T Williams; P Van Eerdewegh; L Almasy; J Blangero
Journal:  Am J Hum Genet       Date:  1999-10       Impact factor: 11.025

2.  Quantitative-trait loci influencing body-mass index reside on chromosomes 7 and 13: the National Heart, Lung, and Blood Institute Family Heart Study.

Authors:  Mary F Feitosa; Ingrid B Borecki; Stephen S Rich; Donna K Arnett; Phyliss Sholinsky; Richard H Myers; Mark Leppert; Michael A Province
Journal:  Am J Hum Genet       Date:  2001-11-16       Impact factor: 11.025

3.  Influence of tumour necrosis factor microsatellite polymorphisms on susceptibility to head and neck cancer.

Authors:  C Matthias; V Jahnke; A Fryer; R Strange; W Ollier; A Hajeer
Journal:  Acta Otolaryngol       Date:  1998-03       Impact factor: 1.494

4.  Late Pleistocene Desiccation of Lake Victoria and Rapid Evolution of Cichlid Fishes

Authors: 
Journal:  Science       Date:  1996-08-23       Impact factor: 47.728

5.  Associations of candidate loci angiotensinogen and angiotensin-converting enzyme with severe hypertension: The NHLBI Family Heart Study.

Authors:  I B Borecki; M A Province; E H Ludwig; R C Ellison; A R Folsom; G Heiss; J M Lalouel; M Higgins; D C Rao
Journal:  Ann Epidemiol       Date:  1997-01       Impact factor: 3.797

6.  Synergistic effect between apolipoprotein E and angiotensinogen gene polymorphisms in the risk for early myocardial infarction.

Authors:  A Batalla; R Alvarez; J R Reguero; S Hevia; G Iglesias-Cubero; V Alvarez; A Cortina; P González; M M Celada; A Medina; E Coto
Journal:  Clin Chem       Date:  2000-12       Impact factor: 8.327

7.  A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2.

Authors:  A G Comuzzie; J E Hixson; L Almasy; B D Mitchell; M C Mahaney; T D Dyer; M P Stern; J W MacCluer; J Blangero
Journal:  Nat Genet       Date:  1997-03       Impact factor: 38.330

8.  Coronary heart disease prediction from lipoprotein cholesterol levels, triglycerides, lipoprotein(a), apolipoproteins A-I and B, and HDL density subfractions: The Atherosclerosis Risk in Communities (ARIC) Study.

Authors:  A R Sharrett; C M Ballantyne; S A Coady; G Heiss; P D Sorlie; D Catellier; W Patsch
Journal:  Circulation       Date:  2001-09-04       Impact factor: 29.690

9.  Genome scan for quantitative trait loci linked to high-density lipoprotein cholesterol: The NHLBI Family Heart Study.

Authors:  J M Peacock; D K Arnett; L D Atwood; R H Myers; H Coon; S S Rich; M A Province; G Heiss
Journal:  Arterioscler Thromb Vasc Biol       Date:  2001-11       Impact factor: 8.311

10.  A genome-wide scan for coronary heart disease suggests in Indo-Mauritians a susceptibility locus on chromosome 16p13 and replicates linkage with the metabolic syndrome on 3q27.

Authors:  S Francke; M Manraj; C Lacquemant; C Lecoeur; F Leprêtre; P Passa; A Hebe; L Corset; S L Yan; S Lahmidi; S Jankee; T K Gunness; U S Ramjuttun; V Balgobin; C Dina; P Froguel
Journal:  Hum Mol Genet       Date:  2001-11-15       Impact factor: 6.150

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