Literature DB >> 11928821

Post-transcriptional regulation of gene expression in the plasminogen activation system.

Nunzia Montuori1, Guido Rossi, Pia Ragno.   

Abstract

The urokinase-mediated plasminogen activation (PA) system has been shown to play a key role in cell migration and tissue invasion by regulating both cell-associated proteolysis and cell-cell and cell-matrix interactions. The expression and activity of the components of this complex system are strictly regulated. The control of the expression occurs both at transcriptional and post-transcriptional levels. This review is focused on the post-transcriptional regulation of gene expression of all components of the PA system.

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Year:  2002        PMID: 11928821     DOI: 10.1515/BC.2002.005

Source DB:  PubMed          Journal:  Biol Chem        ISSN: 1431-6730            Impact factor:   3.915


  7 in total

1.  Involvement of miR-30c and miR-301a in immediate induction of plasminogen activator inhibitor-1 by placental growth factor in human pulmonary endothelial cells.

Authors:  Nitin Patel; Stanley M Tahara; Punam Malik; Vijay K Kalra
Journal:  Biochem J       Date:  2011-03-15       Impact factor: 3.857

2.  Identification of uPAR Variants Acting as ceRNAs in Leukaemia Cells.

Authors:  Mariaevelina Alfieri; Anna Li Santi; Luigia Meo; Valentina Giudice; Carmine Selleri; Pia Ragno
Journal:  Cancers (Basel)       Date:  2022-04-14       Impact factor: 6.575

3.  Helicobacter pylori infection stimulates plasminogen activator inhibitor 1 production by gastric epithelial cells.

Authors:  A C Keates; S Tummala; R M Peek; E Csizmadia; B Kunzli; K Becker; P Correa; J Romero-Gallo; M B Piazuelo; S Sheth; C P Kelly; S C Robson; S Keates
Journal:  Infect Immun       Date:  2008-06-02       Impact factor: 3.441

4.  Angiotensin II induces renal plasminogen activator inhibitor-1 and cyclooxygenase-2 expression post-transcriptionally via activation of the mRNA-stabilizing factor human-antigen R.

Authors:  Anke Doller; Stefan Gauer; Ewelina Sobkowiak; Helmut Geiger; Josef Pfeilschifter; Wolfgang Eberhardt
Journal:  Am J Pathol       Date:  2009-02-26       Impact factor: 4.307

5.  Urokinase receptor and CXCR4 are regulated by common microRNAs in leukaemia cells.

Authors:  Daniela Alfano; Anna Gorrasi; Anna Li Santi; Patrizia Ricci; Nunzia Montuori; Carmine Selleri; Pia Ragno
Journal:  J Cell Mol Med       Date:  2015-06-16       Impact factor: 5.310

6.  Transforming growth factor-Beta and urokinase-type plasminogen activator: dangerous partners in tumorigenesis-implications in skin cancer.

Authors:  Juan F Santibanez
Journal:  ISRN Dermatol       Date:  2013-07-18

7.  A novel oncogenic role for urokinase receptor in leukemia cells: molecular sponge for oncosuppressor microRNAs.

Authors:  Anna Li Santi; Anna Gorrasi; Mariaevelina Alfieri; Nunzia Montuori; Pia Ragno
Journal:  Oncotarget       Date:  2018-06-12
  7 in total

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