Literature DB >> 11924136

Chemonucleolysis of lumbar disc herniation with ethanol.

C Riquelme1, M Musacchio, F Mont'Alverne, A Tournade.   

Abstract

PURPOSE: To demonstrate the efficiency of the treatment of the lumbar disk herniation (LDH) with absolute alcohol. MATERIALS/
METHODS: From June 1997 to September 2000, 118 patients with 126 LDH, 69 males and 49 females, aged 19 to 77 (mean age: 51.1 years) were treated with absolute alcohol nucleolysis. In 75 cases, the LDH were parasagittal, in 30 foraminal, in 17 medial and in 4 extraforaminal. In most cases, the sensitive symptoms and motor or reflex abnormalities corresponded to the lumbar disc herniation level. Nucleolysis was made in ambulatory condition and each patient underwent general anesthesia. All procedures were performed in surgical conditions and controlled under digital fluoroscopy. The disc puncture was laterally made at the junction of middle and posterior thirds of the disc, under strict lateral fluoroscopic control. A discogram was obtained before ethanol injection. Injection dose of absolute alcohol was 0.4 ml. The realization time was about 15 minutes. RESULT: Total improvement of symptoms was obtained in 97.55% of cases. Two patients remained with low-back pain and the failure treatment rate was 0.84% (1 case).
CONCLUSION: Nucleolysis with ethanol is a very effective, safe and low cost treatment for any kind of LDH, that allows to treat several levels during the same procedure, and can be repeated several times. Nucleolysis with ethanol can be made in ambulatory condition and be proposed to patients who refuse surgical treatment and have allergic background.

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Year:  2001        PMID: 11924136

Source DB:  PubMed          Journal:  J Neuroradiol        ISSN: 0150-9861            Impact factor:   3.447


  8 in total

Review 1.  [Nucleolysis in the herniated disk].

Authors:  T Lehnert; S Mundackatharappel; W Schwarz; S Bisdas; A Wetter; C Herzog; J O Balzer; M G Mack; T J Vogl
Journal:  Radiologe       Date:  2006-06       Impact factor: 0.635

2.  Cohort study of lumbar percutaneous chemonucleolysis using ethanol gel in sciatica refractory to conservative treatment.

Authors:  Sébastien Touraine; Joël Damiano; Olivia Tran; Jean-Denis Laredo
Journal:  Eur Radiol       Date:  2015-04-23       Impact factor: 5.315

3.  Percutaneous treatment of cervical disk hernias using gelified ethanol.

Authors:  J Theron; H Cuellar; T Sola; L Guimaraens; A Casasco; P Courtheoux
Journal:  AJNR Am J Neuroradiol       Date:  2010-01-06       Impact factor: 3.825

4.  A minimally invasive treatment for lumbar disc herniation: DiscoGel® chemonucleolysis in patients unresponsive to chemonucleolysis with oxygen-ozone.

Authors:  S Stagni; F de Santis; L Cirillo; M Dall'olio; C Princiotta; L Simonetti; A Stafa; M Leonardi
Journal:  Interv Neuroradiol       Date:  2012-03-16       Impact factor: 1.610

Review 5.  Treatment of chronic low back pain - new approaches on the horizon.

Authors:  Nebojsa Nick Knezevic; Shane Mandalia; Jennifer Raasch; Ivana Knezevic; Kenneth D Candido
Journal:  J Pain Res       Date:  2017-05-10       Impact factor: 3.133

6.  Cervical Discogenic Pain Treatment with Percutaneous Jellified Ethanol: Preliminary Experience.

Authors:  Haytham Eloqayli
Journal:  Biomed Res Int       Date:  2019-03-13       Impact factor: 3.411

7.  Efficacy and durability of radiopaque gelified ethanol in management of herniated discs.

Authors:  Dimitrij Kuhelj; Anita Dobrovolec; Igor Jozef Kocijancic
Journal:  Radiol Oncol       Date:  2019-06-01       Impact factor: 2.991

8.  Effects on pain of percutaneous treatment of cervical disc herniations using DiscoGel: A retrospective analysis.

Authors:  Roberto Fiori; Marco Forcina; Carlo Di Donna; Luigi Spiritigliozzi; Armando Ugo Cavallo; Roberto Floris
Journal:  Neuroradiol J       Date:  2021-03-08
  8 in total

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