| Literature DB >> 11922781 |
Shinya Oishi1, Ayumu Niida, Takae Kamano, Yoshihiko Odagaki, Hirokazu Tamamura, Akira Otaka, Nobuyuki Hamanaka, Nobutaka Fujii.
Abstract
[reaction: see text] A straightforward synthetic route for the synthesis of diastereomerically pure psi[(E)-CMe=CH]- and psi[(E)-CMe=CMe]-type dipeptide isosteres was developed on the basis of regio- and stereoselective anti-S(N)2' alkylation of 3-(N-Boc-5-methyl-4-substituted-oxazolidin-2-on-5-yl)acrylates with organocopper reagents.Entities:
Mesh：
Substances：
Year: 2002 PMID： 11922781 DOI： 10.1021/ol016835b
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005